Detail projektu

Vliv tribologických procesů na životnost náhrad kolenního kloubu

Období řešení: 01.06.2017 — 31.12.2020

Zdroje financování

Ministerstvo školství, mládeže a tělovýchovy ČR - INTER-EXCELLENCE - Podprogram INTER-ACTION

- plně financující (2017-06-01 - 2020-12-31)

O projektu

Počet operací náhrady kolenního kloubu neustále narůstá. Přesto je i v dnešní době stále významným problémem omezená životnost náhrad, kdy je nutné v případě jejich selhání provést revizní operaci. Ta představuje významný zásah do kvality života pacienta. Mezi nejčastější příčiny vedoucí k selhání náhrady patří aseptické uvolnění v důsledku osteolýzy. Jedná se o degradační proces, při kterém dochází k zánětlivé reakci uvolněných otěrových částic a okolní tkáně. Opotřebení artikulujících ploch, které bezprostředně souvisí s procesy tření a mazání, tak představuje z hlediska životnosti náhrady zásadní problém. Při snaze omezit míru otěru a v konečném důsledku tak zlepšit kvalitu života pacientů je proto nutné porozumět tribologickým procesům v kontaktu.

Popis anglicky
The aim of this project is to assess the effect of friction, wear and lubrication on the durability of knee joint replacements. The main attention will be paid to the interaction of the mentioned tribological processes in an effort to extend the implants longevity avoiding the necessity of the need of revising operations. American partner has a long-term experience with the investigation of friction and wear, Czech side will provide a fundamental knowledge about the formation of lubricating film. The obtained data will be confronted with the clinical practice as well. Thus, the present project will provide a complementary knowledge about the tribological processes within the contact. Based on the results, the theory of knee joint replacements lubrication will be defined. So far, such a study has not been performed. The Czech institution will be focused on the observation of lubrication processes in the contact of the replacement components. Lubricant film thickness will be determined while the simultaneous observation of protein aggregations and protein adsorption onto rubbing surfaces will be performed. The main attention will be paid to the effect of load, kinematic conditions and the composition of model synovial fluid on lubrication processes. The US collaborator will initially analyse the composition of the synovial fluid of the patients undergoing total knee replacement. Further, the US researchers will analyse friction and wear of implants. Moreover, the results will be confronted with wear analysis of implants retrieved from the patients during the revising operations, allowing the comparison of laboratory and clinical data. One of the sub-aims of the project is to develop a knee joint simulator enabling to apply kinematic and loading conditions respecting the current standards. Moreover, it will allow to observe the contact in-situ. For this purpose, optical methods based on optical interferometry and fluorescent microscopy will be employed.

Klíčová slova
tribologie; náhrada; kolenní kloub

Klíčová slova anglicky
Tribology; replacement; knee joint

Označení

LTAUSA17150

Originální jazyk

čeština

Řešitelé

Hartl Martin, prof. Ing., Ph.D. - hlavní řešitel
Látal Roman, Ing. - spoluřešitel
Nečas David, doc. Ing., Ph.D. - spoluřešitel
Rebenda David, Ing., Ph.D. - spoluřešitel
Svoboda Petr, doc. Ing., Ph.D. - spoluřešitel
Vrbka Martin, prof. Ing., Ph.D. - spoluřešitel

Útvary

Ústav konstruování
- příjemce (01.06.2017 - 31.12.2020)

Výsledky

CHOUDHURY, D.; RANUŠA, M.; FLEMING, R. A.; VRBKA, M.; KŘUPKA, I.; TEETER M. G.; GOSS, J.; ZOU, M. Mechanical Wear and Oxidative Degradation Analysis of Retrieved Ultra High Molecular Weight Polyethylene Acetabular Cups. Journal of the mechanical behavior of biomedical materials, 2018, vol. 79, no. 1, p. 314-323. ISSN: 1751-6161.
Detail

RANUŠA, M.; WIMMER, M.; FULLAM, S.; VRBKA, M.; KŘUPKA, I. Analysis of Friction in Total Knee Prosthesis during a Standard Gait Cycle. Lubricants, 2021, vol. 9, no. 4, p. 1-14. ISSN: 2075-4442.
Detail

NEČAS, D.; VRBKA, M.; KŘUPKA, I.; HARTL, M. The Effect of Kinematic Conditions and Synovial Fluid Composition on the Frictional Behaviour of Materials for Artificial Joints. Materials, 2018, vol. 11, no. 5, p. 1-12. ISSN: 1996-1944.
Detail

REBENDA, D.; ČÍPEK, P.; NEČAS, D.; VRBKA, M.; HARTL, M. Effect of Hyaluronic Acid on Friction of Articular Cartilage. In Engineering Mechanics 2018. First. Praha: Institute of Theretical and Applied Mechanics of the Czech Academy of Sciences, 2018. p. 709-712. ISBN: 978-80-86246-91-8.
Detail

ČÍPEK, P.; REBENDA, D.; NEČAS, D.; VRBKA, M.; KŘUPKA, I. Development of reciprocating tribometer for testing synovial joint. In Engineering Mechanics 2018. Engineering Mechanics .... First edition. Praha: Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences, Prague, 2018. p. 169-172. ISBN: 978-80-86246-88-8. ISSN: 1805-8256.
Detail

ZEMAN, J.; RANUŠA, M.; VRBKA, M.; GALLO, J.; M.; KŘUPKA, I.; HARTL, M. UHMWPE acetabular cup creep deformation during the run-in phase of THA's life cycle. Journal of the mechanical behavior of biomedical materials, 2018, vol. 87, no. 1, p. 30-39. ISSN: 1751-6161.
Detail

NEČAS, D.; VRBKA, M.; GALANDÁKOVÁ, A.; KŘUPKA, I.; HARTL, M. On the observation of lubrication mechanisms within hip joint replacements. Part I: Hard-on-soft bearing pairs. Journal of the mechanical behavior of biomedical materials, 2019, vol. 89, no. 1, p. 237-248. ISSN: 1751-6161.
Detail

NEČAS, D.; VRBKA, M.; GALLO, J.; KŘUPKA, I.; HARTL, M. On the observation of lubrication mechanisms within hip joint replacements. Part II: Hard-on-hard bearing pairs. Journal of the mechanical behavior of biomedical materials, 2019, vol. 89, no. 1, p. 249-259. ISSN: 1751-6161.
Detail

NEČAS, D.; SADECKÁ, K.; VRBKA, M.; GALLO, J.; GALANDÁKOVÁ, A.; KŘUPKA, I.; HARTL, M. Observation of lubrication mechanisms in knee replacement: A pilot study. Biotribology, 2019, vol. 17, no. 2019, p. 1-7. ISSN: 2352-5738.
Detail

ČÍPEK, P.; REBENDA, D.; VRBKA, M.; HARTL, M. OBSERVATION OF LUBRICATION FILM IN SYNOVIAL JOINT. In Proceedings on Engineering Science. Proceedings on Engineering Sciences - 16th International Conference on Tribology. Kragujevac: University of Kragujevac, Faculty of Engineering, 2019. p. 687-692. ISSN: 2620-2832.
Detail

REBENDA, D.; ČÍPEK, P.; VRBKA, M.; KŘUPKA, I. Effect of Hyaluronic Acid Molecular Weight on Friction of Articular Cartilage. In Proceedings on Engineering Sciences - 16th International Conference on Tribology. Proceedings on Engineering Sciences - 16th International Conference on Tribology. Kragujevac: University of Kragujevac, Faculty of Engineering, 2019. p. 693-697. ISSN: 2620-2832.
Detail

RUFAQUA, R.; VRBKA, M.; CHOUDHURY, D.; HEMZAL, D.; REBENDA, D.; KŘUPKA, I.; HARTL, M. Raman spectroscopic analysis of the biochemical reaction of hyaluronic acid in joint replacement. Nashville: 2019.
Detail

ČÍPEK, P.; REBENDA, D.; NEČAS, D.; VRBKA, M.; KŘUPKA, I.; HARTL, M. Visualization of Lubrication Film in Model of Synovial Joint. Tribology in Industry, 2019, vol. 41, no. 3, p. 387-393. ISSN: 0354-8996.
Detail

LU, X.; NEČAS, D.; MENG, Q.; REBENDA, D.; VRBKA, M.; HARTL, M.; JIN, Z. Towards the direct validation of computational lubrication modelling of hip replacements. Tribology International, 2020, vol. 146, no. 6, p. 106240-106240. ISSN: 0301-679X.
Detail

NEČAS, D.; USAMI, H.; NIIMI, T.; SAWAE, Y.; KŘUPKA, I.; HARTL, M. Running-in friction of hip joint replacements can be significantly reduced: The effect of surface-textured acetabular cup. Friction, 2020, vol. 8, no. 6, p. 1137-1152. ISSN: 2223-7690.
Detail

NEČAS, D.; SADECKÁ, K.; VRBKA, M.; GALANDÁKOVÁ, A.; WIMMER, M.A.; GALLO, J.; HARTL, M. The Effect of Albumin and γ-globulin on Synovial Fluid Lubrication: Implication for Knee Joint Replacements. Journal of the mechanical behavior of biomedical materials, 2021, vol. 113, no. 1, p. 104117-104117. ISSN: 1751-6161.
Detail

NEČAS, D.; VRBKA, M.; MARIAN, M.; ROTHAMMER, B.; TREMMEL, S.; WARTZACK, S.; GALANDÁKOVÁ, A.; GALLO, J.; WIMMER, M.; KŘUPKA, I.; HARTL, M. Towards the Understanding of Lubrication Mechanisms in Total Knee Replacements – Part I: Experimental Investigations. Tribology International, 2021, vol. 156, no. 4, p. 106874-106874. ISSN: 0301-679X.
Detail

MARIAN, M.; ORGELDINGER, C.; ROTHAMMER, R.; NEČAS, D.; VRBKA, M.; KŘUPKA, I.; HARTL, M.; WIMMER, M.A.; TREMMEL, S.; WARTZACK, S. Towards the Understanding of Lubrication Mechanisms in Total Knee Replacements – Part II: Numerical Modeling. Tribology International, 2021, vol. 156, no. 4, p. 106809-106809. ISSN: 0301-679X.
Detail

R. Rufaqua, M. Vrbka, D. Choudhury, D. Hemzal, I. Křupka, M. Hartl. THE BIOCHEMICAL PROCESS OF LUBRICANT FILM FORMATION IN JOINT REPLACEMENT. In Engineering Mechanics 2018. First. Praha: Institute of Theretical and Applied Mechanics of the Czech Academy of Sciences, 2018. p. 725-728. ISBN: 978-80-86246-88-8.
Detail

POLNICKÝ, V.; VRBKA, M.; NEČAS, D.; RANUŠA, M.; REBENDA, D.: Simulátor kolenního kloubu; Simulátor kolenního kloubu s proměnnými kinematickými a zátěžnými podmínkami. Laboratoř tribologie A2/402 Ústav konstruování Fakulta strojního inženýrství Vysoké učení technické v Brně Technická 2896/2 616 69 Brno. URL: http://pom.uk.fme.vutbr.cz/pdf_projekt.php?id=366. (funkční vzorek)
Detail

Odpovědnost: Hartl Martin, prof. Ing., Ph.D.