Detail projektu

Design and analysis of novel extracellular matrix mimicking materials with tailored internal architecture targeted for drug delivery systems

Období řešení: 01.02.2021 — 31.01.2022

Zdroje financování

Evropská unie - Interní grantová soutěž

- plně financující (2021-02-01 - 2022-01-31)

O projektu

Proposed project focuses on design of biopolymer network with internal structure modified by self-assembly of phospholipid (lecithin) with the potential use as novel extracellular matrix (ECM) model in drug delivery systems. This project takes aim to precisely characterize application-relevant properties (structural for xerogels, transport and mechanical for hydrogels) and their mutual interconnections to evaluate potential usage of these novel materials in biomedical application.

Popis anglicky
The aim of the project is to create a competition for student research grants and its pilot verification. The creation of a new competition will contribute to the development of cross-sectional skills of doctoral students, and thus acquire competencies for work in science and research in the future and increase their success in submitting scientific projects to national and international competitions.

Označení

FCH-K-21-7056

Originální jazyk

čeština

Řešitelé

Heger Richard, Ing., Ph.D. - hlavní řešitel
Kadlec Martin, Ing. - spoluřešitel
Trudičová Monika, Ing., Ph.D. - spoluřešitel
Zinkovska Natalia, Ing. - spoluřešitel

Útvary

Fakulta chemická
- příjemce (01.02.2021 - 31.01.2022)

Výsledky

HEGER, R.; KADLEC, M.; ZINKOVSKA, N.; TRUDIČOVÁ, M.; SMILEK, J. Lecithin as internal architecture modifier of hydrogels for model drug delivery systems with tunable properties. 35th Conference of the European Colloid & Interface Society, Book of Abstracts (Poster Presentations). 2021. p. 255-255.
Detail

HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; HAJZLER, J.; PEKAŘ, M.; SMILEK, J. Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach. Gels, 2022, vol. 8, no. 2, p. 1-23. ISSN: 2310-2861.
Detail

ZINKOVSKA, N.; HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; SMILEK, J. How the presence of lecithin nanodomains affects the transport properties of hydrogels - potential controlled release drug delivery. Nanocon 2021 - Abstracts. Ostrava, CZ: Tanger Ltd., 2021. p. 95-95. ISBN: 978-80-88365-00-6.
Detail

HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; SMILEK, J. Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains. Nanocon 2021 - Abstracts. Ostrava, CZ: Tanger Ltd., 2021. p. 96-96. ISBN: 978-80-88365-00-6.
Detail

Odpovědnost: Heger Richard, Ing., Ph.D.