patent

The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acid addition salt, to compounds of formula (11) and (14), processes of making them and to their use in making fingolimod.

WO2012041405A1

22. 12. 2010

5. 4. 2012

Úřad průmyslového vlastnictví (patentový úřad České republiky)

SYNTHON B.V. Microweg 22 NL-6545 CM Nijmegen

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