Detail publikace

The Effect of Cadmium Ions and Cadmium Nanoparticles on Chicken Embryos and Evaluation of Organ Accumulation

KENŠOVÁ, R. BLAŽKOVÁ, I. VACULOVIČOVÁ, M. MILOSAVLJEVIĆ, V. BLAŽKOVÁ, L. HYNEK, D. KOPEL, P. NOVOTNÁ, M. ZEHNÁLEK, J. POHANKA, M. TRNKOVÁ, L. ADAM, V. KIZEK, R.

Originální název

The Effect of Cadmium Ions and Cadmium Nanoparticles on Chicken Embryos and Evaluation of Organ Accumulation

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The presence of metals in the organism has both positive and negative influence on the functions of the body, depending on the concentration. Cadmium is one of the metals that have irrefutable negative effect. It is highly toxic metal with long biological half-life causing damage of kidneys, bones and has carcinogenic effect. The aim of this work was the study of the effect and distribution of the cadmium in the body and its comparison with cadmium nanoparticles – CdTe quantum dots (QDs). Model organism for these experiments was chicken embryo in 16th developmental day. The distribution of cadmium was analyzed after the application of 500 uL of cadmium solution (Cd ions) in concentration 1 mg/mL or 4.5 mg/mL). This solution was applied through the small hole in the egg shell onto the chorioallantoic membrane. After 24 hours of the incubation (37.5 C, 45% rH) liver, kidney, brain and hearth were extracted. The concentration of cadmium was analyzed after the mineralization of the samples by atomic absorption spectrometry and differential pulse voltammetry. The toxicity of cadmium solution was significantly higher compared to the solution of QDs. Embryos exposed to the cadmium ions exhibited 100% mortality after 24 hours. On the contrary, the mortality of embryos exposed to QDs was 0%. The highest levels of cadmium were detected in the kidneys (125 ug per g) and in the liver (107 ug per g).

Klíčová slova

Cadmium; Quantum Dots; Chicken embryos; Tissue; Distribution; Atomic absorption spectroscopy; Differential pulse voltammetry

Autoři

KENŠOVÁ, R.; BLAŽKOVÁ, I.; VACULOVIČOVÁ, M.; MILOSAVLJEVIĆ, V.; BLAŽKOVÁ, L.; HYNEK, D.; KOPEL, P.; NOVOTNÁ, M.; ZEHNÁLEK, J.; POHANKA, M.; TRNKOVÁ, L.; ADAM, V.; KIZEK, R.

Rok RIV

2015

Vydáno

1. 4. 2015

Nakladatel

ESG

ISSN

1452-3981

Periodikum

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE

Ročník

10

Číslo

4

Stát

Srbská republika

Strany od

3623

Strany do

3634

Strany počet

12

URL

http://www.electrochemsci.org/papers/vol10/100403623.pdf

Plný text v Digitální knihovně

http://hdl.handle.net/11012/201453

BibTex

@article{BUT114334,
  author="Renáta {Kenšová} and Iva {Blažková} and Markéta {Vaculovičová} and Vedran {Milosavljević} and Lucie {Blažková} and David {Hynek} and Pavel {Kopel} and Marie {Novotná} and Josef {Zehnálek} and Miroslav {Pohanka} and Libuše {Trnková} and Vojtěch {Adam} and René {Kizek}",
  title="The Effect of Cadmium Ions and Cadmium Nanoparticles on Chicken Embryos and Evaluation of Organ Accumulation",
  journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE",
  year="2015",
  volume="10",
  number="4",
  pages="3623--3634",
  issn="1452-3981",
  url="http://www.electrochemsci.org/papers/vol10/100403623.pdf"
}