Detail publikace

Combination of X-ray micro-Computed tomography and laser-ablation based analytical techniques for 3D high resolution elemental mapping

TESAŘOVÁ, M. POŘÍZKA, P. ŠEJNOHOVÁ, M. ZIKMUND, T. NOVOTNÝ, K. SANCEY, L. MOTTO-ROS, V. TILLEMENT, O. KAISER, J.

Originální název

Combination of X-ray micro-Computed tomography and laser-ablation based analytical techniques for 3D high resolution elemental mapping

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Detection and chemical 3D mapping of nanoparticles (NPs) distribution in biospecimen is a challenging task that can be met by simultaneous utilization of imaging techniques. Here we focus on the synergy of X-Ray micro-Computed Tomography (μCT), Laser-Induced Breakdown Spectroscopy (LIBS) and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) for investigation of various nanoparticles (Gd, Ti, Pb, etc.) distributed in organs. Special emphasis is given to the analysis of nanoparticles in a murine kidney in 3D. Firstly, we have demonstrated the 3D visualization capabilities in soft tissues by iodine staining with μCT. Next, subsequent LIBS and LA-ICP-MS analysis enabled to identify nanoparticles distribution in the sample. Thus, this combination provides a novel analytical approach how to quickly visualize and recognize different elements in soft tissues.

Klíčová slova

Nanoparticles; 3D mapping; Computed Tomography; Laser-Induced Breakdown Spectroscopy; Laser Ablation Inductively Coupled Plasma Mass Spectrometry

Autoři

TESAŘOVÁ, M.; POŘÍZKA, P.; ŠEJNOHOVÁ, M.; ZIKMUND, T.; NOVOTNÝ, K.; SANCEY, L.; MOTTO-ROS, V.; TILLEMENT, O.; KAISER, J.

Vydáno

19. 10. 2016

ISBN

978-80-904959-4-4

Kniha

13th International Interdisciplinary Meeting on Bioanalysis

Číslo edice

13

Strany od

253

Strany do

255

Strany počet

3

BibTex

@inproceedings{BUT130420,
  author="Markéta {Kaiser} and Pavel {Pořízka} and Marie {Šejnohová} and Tomáš {Zikmund} and Karel {Novotný} and Lucie {Sancey} and Vincent {Motto-Ros} and Olivier {Tillement} and Jozef {Kaiser}",
  title="Combination of X-ray micro-Computed tomography and laser-ablation based analytical techniques for 3D high resolution elemental mapping",
  booktitle="13th International Interdisciplinary Meeting on Bioanalysis",
  year="2016",
  number="13",
  pages="253--255",
  isbn="978-80-904959-4-4"
}