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VELCER, T. PEKAŘ, M.
Originální název
Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant
Typ
abstrakt
Jazyk
angličtina
Originální abstrakt
This study deals with the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. Using the method of rheology, the fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of hyaluronan has also direct influence on the volume and stiffness of the newly formed hydrogels. Preparation methods were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The results of this study indicate that given gels are to a certain extent competitive and incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.
Klíčová slova
hyaluronan, surfactants, hydrogels, rheology
Autoři
VELCER, T.; PEKAŘ, M.
Vydáno
23. 3. 2017
Nakladatel
Vysoké učení technické v Brně, Fakulta chemická
Místo
Brno
ISBN
978-80-214-5488-0
Kniha
Sborník abstraktů
Edice
1.
Číslo edice
první
Strany od
93
Strany do
Strany počet
1
BibTex
@misc{BUT141492, author="Tomáš {Velcer} and Miloslav {Pekař}", title="Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant", booktitle="Sborník abstraktů", year="2017", series="1.", edition="první", pages="93--93", publisher="Vysoké učení technické v Brně, Fakulta chemická", address="Brno", isbn="978-80-214-5488-0", note="abstract" }