Detail publikace

THE USE OF NANOTECHNOLOGY AS MODERN TOOLS TO TREAT INFECTIONS CAUSED BY MULTIRESISTANT BACTERIA STRAINS

SKLENÁŘ, M. CHUDOBOVA, D. RUTTKAY-NEDECKÝ, B. KRYŠTOFOVÁ, O. KOPEL, P. ADAM, V. KIZEK, R.

Originální název

THE USE OF NANOTECHNOLOGY AS MODERN TOOLS TO TREAT INFECTIONS CAUSED BY MULTIRESISTANT BACTERIA STRAINS

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

This work focuses on development of antimicrobial complex substances, suitable to cover vascular implants with the secondary use in transplantation surgery. This work also presents a comparison of the effects of used nanomaterials against ordinary substances. The formation of complexes took place between silver nanoparticles, silver ions and the polymer substances (hyaluronic acid, collagen and chitosan). The ability of complex formation of these substances was studied using electrochemistry and spectrophotometry. Bactericidal effect of these compounds was determined by growth-curve methods and inhibition zones on a bacterial culture Staphylococcus aureus. The viability of eukaryotic cells in straight confrontation with tested substances was observed using the MTT test. According to the data obtained, the complex of silver nanoparticles with chitosan was evaluated as the best substance to ensure antimicrobial behaviour of vascular implants.

Klíčová slova

microbiology; spectrophotometry; electrochemistry; nanotechnology; resistant microorganisms

Autoři

SKLENÁŘ, M.; CHUDOBOVA, D.; RUTTKAY-NEDECKÝ, B.; KRYŠTOFOVÁ, O.; KOPEL, P.; ADAM, V.; KIZEK, R.

Vydáno

21. 11. 2013

ISBN

978-80-7375-908-7

Kniha

MENDELNET 2013

Strany od

929

Strany do

933

Strany počet

5

BibTex

@inproceedings{BUT143590,
  author="Matěj {Sklenář} and Dagmar {chudobova} and Branislav {Ruttkay-Nedecký} and Olga {Kryštofová} and Pavel {Kopel} and Vojtěch {Adam} and René {Kizek}",
  title="THE USE OF NANOTECHNOLOGY AS MODERN TOOLS TO TREAT INFECTIONS CAUSED BY MULTIRESISTANT BACTERIA STRAINS",
  booktitle="MENDELNET 2013",
  year="2013",
  pages="929--933",
  isbn="978-80-7375-908-7"
}