Detail publikace

Monitoring Progress of Parkinson’s Disease Based on Changes in Phonation: a Pilot Study

GALÁŽ, Z. MEKYSKA, J. KISKA, T. ZVONČÁK, V. MUCHA, J. HARÁR, P. SMÉKAL, Z. ELIÁŠOVÁ, I. MRAČKOVÁ, M. KOŠŤÁLOVÁ, M. REKTOROVÁ, I. ALONSO-HERNANDEZ, J. GOMEZ-VILDA, P.

Originální název

Monitoring Progress of Parkinson’s Disease Based on Changes in Phonation: a Pilot Study

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Hypokinetic dysarthria (HD) is a frequent symptom of idiopathic Parkinson’s disease (PD). Although it is hypothesized its progress is tightly linked with changes in other motor/non-motor features of PD, it has not been proved yet. The aim of this work is to employ acoustic analysis of sustained phonation in order to identify significant correlates between phonatory measures and motor/non-motor deficits in a two-year follow-up study. For this purpose, we repeatedly quantified a sustained vowel /a/ in 51 PD patients who were also assessed by 5 common clinical scales. In addition, a multivariate regression model was trained to predict the motor/non-motor deficits in the horizon of two years. Results suggest that mainly instability in vocal folds oscillation increases with the progress of PD and with overall cognitive decline. Based on the acoustic analysis, the change in clinical scores could be predicted with the error in the range of 11.83–19.60 %.

Klíčová slova

acoustic analysis; follow-up study; hypokinetic dysarthria; Parkinson’s disease; phonation

Autoři

GALÁŽ, Z.; MEKYSKA, J.; KISKA, T.; ZVONČÁK, V.; MUCHA, J.; HARÁR, P.; SMÉKAL, Z.; ELIÁŠOVÁ, I.; MRAČKOVÁ, M.; KOŠŤÁLOVÁ, M.; REKTOROVÁ, I.; ALONSO-HERNANDEZ, J.; GOMEZ-VILDA, P.

Vydáno

4. 6. 2018

Nakladatel

Institute of Electrical and Electronics Engineers Inc.

Místo

Atény, Řecko

ISBN

978-1-5386-4695-3

Kniha

41st International Conference on Telecommunications and Signal Processing (TSP)

Strany od

218

Strany do

221

Strany počet

4

URL

https://ieeexplore.ieee.org/document/8441307

BibTex

@inproceedings{BUT148853,
  author="Zoltán {Galáž} and Jiří {Mekyska} and Tomáš {Kiska} and Vojtěch {Zvončák} and Ján {Mucha} and Pavol {Harár} and Zdeněk {Smékal} and Ilona {Eliášová} and Martina {Mračková} and Milena {Košťálová} and Irena {Rektorová} and Jesus {Alonso-Hernandez} and Pedro {Gomez-Vilda}",
  title="Monitoring Progress of Parkinson’s Disease Based
on Changes in Phonation: a Pilot Study",
  booktitle="41st International Conference on Telecommunications and Signal Processing (TSP)",
  year="2018",
  pages="218--221",
  publisher="Institute of Electrical and Electronics Engineers Inc.",
  address="Atény, Řecko",
  doi="10.1109/TSP.2018.8441307",
  isbn="978-1-5386-4695-3",
  url="https://ieeexplore.ieee.org/document/8441307"
}