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KOLESA, P. KLUČÁKOVÁ, M. GAVENDA, A.
Originální název
STUDY OF FLOW PROPERTIES OF POWDERS IN PHARMACEUTICAL INDUSTRY
Typ
článek ve sborníku mimo WoS a Scopus
Jazyk
angličtina
Originální abstrakt
The main purpose of presented work is study of two model batches of APIs which were characterized by different flow properties (especially different tendency to caking). Immunosuppressant drug Mycophenolic Acid (MPA) was chosen such as model substance for this study, because this API caused large troubles in production due to presence of large lumps which clogged the hopper and it was very difficult to transport the sample through the pipeline. This issue had an adverse impact on production efficiency and it was necessary to find the relevant properties and parameters which affect lumps creation. Therefore many physico-chemical techniques were used for characterization of chosen batches of MPA.
Klíčová slova
API; flowability; caking; polymorphism; handling
Autoři
KOLESA, P.; KLUČÁKOVÁ, M.; GAVENDA, A.
Vydáno
11. 12. 2018
Nakladatel
Czech Chemical Society
Místo
Prague
ISBN
2336-7210
Kniha
Czech Chemical Society Symposium Series
ISSN
Periodikum
Ročník
16
Číslo
6
Stát
Česká republika
Strany od
498
Strany do
503
Strany počet
528
URL
http://www.ccsss.cz/index.php/ccsss/issue/view/18/showToc
BibTex
@inproceedings{BUT156062, author="Pavel {Kolesa} and Martina {Klučáková} and Aleš {Gavenda}", title="STUDY OF FLOW PROPERTIES OF POWDERS IN PHARMACEUTICAL INDUSTRY", booktitle="Czech Chemical Society Symposium Series", year="2018", journal="Czech Chemical Society Symposium Series", volume="16", number="6", pages="498--503", publisher="Czech Chemical Society", address="Prague", isbn="2336-7210", issn="2336-7210", url="http://www.ccsss.cz/index.php/ccsss/issue/view/18/showToc" }