Detail publikace

The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

REJMONTOVÁ, P., KOVALČÍK, A., HUMPOLÍČEK, P., CAPÁKOVÁ, Z., WRZECIONKO, E., SÁHA, P.

Originální název

The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The mechanical properties of poly(vinyl alcohol) (PVA)-based scaffolds were successfully improved. The improvements in mechanical properties correlated with the amount of Kraft lignin in PVA matrices. The critical property for any scaffold is its capacity to allow cells to ingrow and survive within its internal structure. The ingrowth of cells was tested using bioreactors creating simulated in vivo conditions. In the context of all the mentioned parameters, the most advantageous properties were exhibited by the scaffold containing 99 wt% PVA and 1 wt% Kraft lignin. The composites with 1 wt% Kraft lignin exhibited sufficient mechanical stability, a lack of cytotoxicity, and mainly the ability to allow the ingrowth of cells into the scaffold in a rotation bioreactor.

Klíčová slova

cytotoxicity; lignin; mechanical properties; poly(vinyl alcohol); scaffolds,

Autoři

REJMONTOVÁ, P., KOVALČÍK, A., HUMPOLÍČEK, P., CAPÁKOVÁ, Z., WRZECIONKO, E., SÁHA, P.

Vydáno

23. 4. 2019

Nakladatel

The Royal Society of Chemistry

ISSN

2046-2069

Periodikum

RSC Advances

Ročník

9

Číslo

1

Stát

Spojené království Velké Británie a Severního Irska

Strany od

12346

Strany do

12353

Strany počet

8

URL

https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra09757g#!divAbstract

Plný text v Digitální knihovně

http://hdl.handle.net/11012/194738

BibTex

@article{BUT157312,
  author="Petra {Rejmontová} and Adriána {Kovalčík} and Petr {Humpolíček} and Zdenka {Capáková} and Erik {Wrzecionko} and Petr {Sáha}",
  title="The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds",
  journal="RSC Advances",
  year="2019",
  volume="9",
  number="1",
  pages="12346--12353",
  doi="10.1039/C8RA09757G",
  issn="2046-2069",
  url="https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra09757g#!divAbstract"
}

Dokumenty

scan0019.pdf