Detail publikace

Cytotoxicity of Shear Exfoliated Pnictogen (As, Sb, Bi) Nanosheets

CHIA, H. LATIFF, N. GUSMÃO, R. SOFER, Z. PUMERA, M.

Originální název

Cytotoxicity of Shear Exfoliated Pnictogen (As, Sb, Bi) Nanosheets

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The experimental achievement of phosphorene, which exhibits superior electronic, physical, and optical properties has spurred recent interest in other Group 15 elemental 2D nanomaterials such as arsenene, antimonene, and bismuthene. These unique and superior properties of the pnictogen nanosheets have spurred intensive research efforts and led to the discovery of their diversified potential applications; for instance, optical Kerr material, photonic devices, pnictogen-decorated microfibers, high-speed transistors, and flexible 2D electronics. Previous studies have mainly been dedicated to study the synthesis, properties, and applications of the heavy pnictogens nanosheets; however, the toxicological behaviour of these nanosheets has yet to be established. Herein, the cytotoxicity study of pnictogen nanosheets (As, Sb, and B) was conducted over 24 h of incubation with various concentrations of test materials and adenocarcinoma human lung epithelial A549 cells. After the treatment period, the remaining cell viabilities were obtained through absorbance measurements with WST-8 and MTT assays. These findings demonstrate that the toxicity of pnictogen nanosheets decreases down Group 15, whereby arsenic nanosheets are considered to be the most toxic, whereas bismuth nanosheets induce low cytotoxicity. The findings of this study constitute an important initial step towards enhancing our understanding of the toxicological effects of pnictogen nanosheets in light of their prospective commercial applications.

Klíčová slova

cell viability; cytotoxicity; layered materials; phosphorene; pnictogen nanosheets

Autoři

CHIA, H.; LATIFF, N.; GUSMÃO, R.; SOFER, Z.; PUMERA, M.

Vydáno

11. 2. 2019

ISSN

0947-6539

Periodikum

CHEMISTRY-A EUROPEAN JOURNAL

Ročník

25

Číslo

9

Stát

Spolková republika Německo

Strany od

2242

Strany do

2249

Strany počet

8

URL

https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201804336

BibTex

@article{BUT158444,
  author="Hui Ling {Chia} and Naziah Mohamad {Latiff} and Rui {Gusmão} and Zdeněk {Sofer} and Martin {Pumera}",
  title="Cytotoxicity of Shear Exfoliated Pnictogen (As, Sb, Bi) Nanosheets",
  journal="CHEMISTRY-A EUROPEAN JOURNAL",
  year="2019",
  volume="25",
  number="9",
  pages="2242--2249",
  doi="10.1002/chem.201804336",
  issn="0947-6539",
  url="https://onlinelibrary.wiley.com/doi/full/10.1002/chem.201804336"
}