Detail publikace

Micromotors as "Motherships": A Concept for the Transport, Delivery, and Enzymatic Release of Molecular Cargo via Nanoparticles

KROUPA, T. HERMANOVÁ, S. MAYORGA-MARTINEZ, C. NOVOTNÝ, F. SOFER, Z. PUMERA, M.

Originální název

Micromotors as "Motherships": A Concept for the Transport, Delivery, and Enzymatic Release of Molecular Cargo via Nanoparticles

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Nano/micromotors based on biodegradable and biocompatible polymers represent a progressively developing group of self-propelled artificial devices capable of delivering biologically active compounds to target sites. The majority of these machines are micron sized, and biologically active compounds are simply attached to their surface. Micron-sized devices cannot enter cells, but they provide rapid velocity, which scales down with the size of the device; nanosized devices can enter cells, but their velocity is negligible. An advanced hierarchical design of the micro/nanodevices is an important tool in the development of functional biocompatible transport systems and their implementation in real in vivo applications. In this work, we demonstrate a "mothership" concept, whereby self-propelled microrobots transport smaller cargo-carrying nanorobots that are released by enzymatic degradation.

Klíčová slova

JANUS MICROMOTORS; DRIVEN; MICROFISH; MOBILITY; SENSORS; IMPACT; MOTION

Autoři

KROUPA, T.; HERMANOVÁ, S.; MAYORGA-MARTINEZ, C.; NOVOTNÝ, F.; SOFER, Z.; PUMERA, M.

Vydáno

13. 8. 2019

ISSN

0743-7463

Periodikum

Langmuir

Ročník

35

Číslo

32

Stát

Spojené státy americké

Strany od

10618

Strany do

10624

Strany počet

7

URL

https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.9b01192

BibTex

@article{BUT159810,
  author="Tomáš {Kroupa} and Soňa {Hermanová} and Carmen C. {Mayorga-Martinez} and Filip {Novotný} and Zdeněk {Sofer} and Martin {Pumera}",
  title="Micromotors as {"}Motherships{"}: A Concept for the Transport, Delivery, and Enzymatic Release of Molecular Cargo via Nanoparticles",
  journal="Langmuir",
  year="2019",
  volume="35",
  number="32",
  pages="10618--10624",
  doi="10.1021/acs.langmuir.9b01192",
  issn="0743-7463",
  url="https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.9b01192"
}