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MANAKHOV, A. PERMYAKOVA, E. ERSHOV, S. SHEVEYKO, A. KOVALSKII, A. POLČÁK, J. ZHITNYAK, I. GLOUSHANKOVA, N. ZAJÍČKOVÁ, L. SHTANSKY, D.
Originální název
Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
This work deals with the deposition of bioactive TiCaPCON films onto biodegradable polycaprolactone (PCL) nanofibers using magnetron sputtering for bone tissue engineering. Low melting point of PCL nanofibers requires a careful tuning of processing parameters in order to achieve high film quality and avoid substrate degradation. SEM and XPS analyses showed that, with the magnetron current of 2 A, the TiCaPCON films deposited onto PCL nanofibers and Si wafers exhibit similar chemical states hereby indicating that the nanofiber structure is not affected by the deposition process. In vitro biological tests indicated that the osteoblasts adhesion and proliferation as well the ALP activity can be significantly improved by depositing the TiCaPCON film onto PCL. The reported findings suggest a new strategy for the preparation of biodegradable polymer-based biomaterials for bone tissue engineering.
Klíčová slova
PCL; TiCaPCON; Nanofibers; Magnetron sputtering; XPS; Osteoblast
Autoři
MANAKHOV, A.; PERMYAKOVA, E.; ERSHOV, S.; SHEVEYKO, A.; KOVALSKII, A.; POLČÁK, J.; ZHITNYAK, I.; GLOUSHANKOVA, N.; ZAJÍČKOVÁ, L.; SHTANSKY, D.
Vydáno
15. 6. 2019
Nakladatel
ELSEVIER SCIENCE BV
Místo
AMSTERDAM
ISSN
0169-4332
Periodikum
Applied Surface Science
Ročník
479
Číslo
1
Stát
Nizozemsko
Strany od
796
Strany do
802
Strany počet
7
URL
https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub
BibTex
@article{BUT161050, author="Anton {Manakhov} and Elizaveta {Permyakova} and Sergey {Ershov} and A.N. {Sheveyko} and Andrey {Kovalskii} and Josef {Polčák} and I.Y. {Zhitnyak} and Natalia A. {Gloushankova} and Lenka {Zajíčková} and Dmitry V. {Shtansky}", title="Bioactive TiCaPCON-coated PCL nanofibers as a promising material for bone tissue engineering", journal="Applied Surface Science", year="2019", volume="479", number="1", pages="796--802", doi="10.1016/j.apsusc.2019.02.163", issn="0169-4332", url="https://www.sciencedirect.com/science/article/pii/S0169433219305057?via%3Dihub" }