Detail publikace

Distance-based paper device using polydiacetylene liposome as a chromogenic substance for rapid and in-field analysis of quaternary ammonium compounds

CHUTVIRASAKUL, B. NUCHTAVORN, N. MACKA, M. SUNTORNSUK, L.

Originální název

Distance-based paper device using polydiacetylene liposome as a chromogenic substance for rapid and in-field analysis of quaternary ammonium compounds

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This work presents an affordable distance-based microfluidic paper-based device (mu PAD), using polydiacetylene (PDA) liposome as a chromogenic substance with a smartphone-based photo editor, for rapid and in-field analysis of quaternary ammonium compounds (QACs) (e.g., didecyldimethylammonium chloride (DDAC), benzyldimethyltetradecyl ammonium chloride (BAC), and cetylpyridinium chloride (CPC)). In-field analysis of these compounds is important to ensure their antimicrobial activity and user safety since they are widely utilized as disinfectants in households and hospitals. The mu PAD featured a thermometer-like shape consisting of a sample reservoir and a microchannel as the detection zone, which was pre-deposited with PDA liposome. The color change from blue to red appeared in the presence of QACs and the color bar lengths were proportional to the QAC concentrations. Reactions of QACs with the PDA required a specific pH range (from pH 4.0 to 10.0) and a readout time of 7 min. Analytical performance characteristics of the device were tested with DDAC, BAC, and CPC showing acceptable specificity, accuracy (96.1-109.4%), and precision (%RSDs <= 9.3%). Limits of detection and quantitation were in the ranges of 20 to 80 and 70 to 250 mu M, respectively. Feasibility of the newly developed device was demonstrated for in-field analysis of QACs in fumigation solution providing comparable results with those obtained from a colorimetric assay (P > 0.05). The proposed device shows potentials for further applications of other analytes since it offers speed, simplicity, and affordability for in-field analysis, especially in remote areas where expertise, resources, and infrastructures are limited.

Klíčová slova

Distance-based microfluidic paper-based device; Polydiacetylene; Quaternary ammonium compounds; In-field analysis

Autoři

CHUTVIRASAKUL, B.; NUCHTAVORN, N.; MACKA, M.; SUNTORNSUK, L.

Vydáno

31. 5. 2020

ISSN

1618-2642

Periodikum

Analytical and Bioanalytical Chemistry

Ročník

412

Číslo

13

Stát

Spolková republika Německo

Strany od

3221

Strany do

3230

Strany počet

10

URL

https://doi.org/10.1007/s00216-020-02583-y

BibTex

@article{BUT164510,
  author="CHUTVIRASAKUL, B. and NUCHTAVORN, N. and MACKA, M. and SUNTORNSUK, L.",
  title="Distance-based paper device using polydiacetylene liposome as a chromogenic substance for rapid and in-field analysis of quaternary ammonium compounds",
  journal="Analytical and Bioanalytical Chemistry",
  year="2020",
  volume="412",
  number="13",
  pages="3221--3230",
  doi="10.1007/s00216-020-02583-y",
  issn="1618-2642",
  url="https://doi.org/10.1007/s00216-020-02583-y"
}