Detail publikace

Influence of Hydroxyapatite Nanoparticles and Surface Plasma Treatment on Bioactivity of Polycaprolactone Nanofibers

ŠŤASTNÁ, E. ČÁSTKOVÁ, K. RÁHEĽ, J.

Originální název

Influence of Hydroxyapatite Nanoparticles and Surface Plasma Treatment on Bioactivity of Polycaprolactone Nanofibers

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Nanofibers are well known as a beneficial type of structure for tissue engineering. As a result of the high acquisition cost of the natural polymers and their environmentally problematic treatment (toxic dissolution agents), artificial polymers seem to be the better choice for medical use. In the present study, polycaprolactone nano-sized fibrous structures were prepared by the electrospinning method. The impact of material morphology (random or parallelly oriented fibers versus continuous layer) and the presence of a fraction of hydroxyapatite nanoparticles on cell proliferation was tested. In addition, the effect of improving the material wettability by a low temperature argon discharge plasma treatment was evaluated, too. We have shown that both hydroxyapatite particles as well as plasma surface treatment are beneficial for the cell proliferation. The significant impact of both influences was evident during the first 48 h of the test: the hydroxyapatite particles in polycaprolactone fibers accelerated the proliferation by 10% compared to the control, and the plasma-treated ones enhanced proliferation by 30%.

Klíčová slova

electrospinning; nanofibers; polycaprolactone; hydroxyapatite; tissue engineering; atmospheric pressure argon plasma

Autoři

ŠŤASTNÁ, E.; ČÁSTKOVÁ, K.; RÁHEĽ, J.

Vydáno

20. 8. 2020

Nakladatel

MDPI

Místo

Basel, Švýcarská konfederace

ISSN

2073-4360

Periodikum

Polymers

Ročník

12

Číslo

9

Stát

Švýcarská konfederace

Strany od

1

Strany do

16

Strany počet

16

URL

https://www.mdpi.com/2073-4360/12/9/1877

Plný text v Digitální knihovně

http://hdl.handle.net/11012/194808

BibTex

@article{BUT164786,
  author="Eva {Šťastná} and Klára {Částková} and Jozef {Ráheĺ}",
  title="Influence of Hydroxyapatite Nanoparticles and Surface Plasma Treatment on Bioactivity of Polycaprolactone Nanofibers",
  journal="Polymers",
  year="2020",
  volume="12",
  number="9",
  pages="1--16",
  doi="10.3390/polym12091877",
  issn="2073-4360",
  url="https://www.mdpi.com/2073-4360/12/9/1877"
}