Přístupnostní navigace
E-přihláška
Vyhledávání Vyhledat Zavřít
Detail publikace
BHOWMICK, S. MAZUMDAR, A. MOULICK, A. ADAM, V.
Originální název
Algal Metabolites: An Inevitable Substitute for Antibiotics
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Antibiotic resistance is rising at a pace that is difficult to cope with; circumvention of this issue requires fast and efficient alternatives to conventional antibiotics. Algae inhabit a wide span of ecosystems, which contributes to their ability to synthesize diverse classes of highly active biogenic metabolites. Here, for the first time, we reviewed all possible algal metabolites with broad spectra antibacterial activity against pathogenic bacteria, including antibiotic-resistant strains, and categorized different metabolites of both freshwater and marine algae, linking them on the basis of their target sites and mechanistic actions along with their probable nanoconjugates. Algae can be considered a boon for novel drug discovery in the era of antibiotic resistance, as various algal primary and secondary metabolites possess potential antibacterial properties. The diversity of these metabolites from indigenous sources provides a promising gateway enabling researchers and pharmaceutical companies to develop novel nontoxic, cost-effective and highly efficient antibacterial medicines.
Klíčová slova
Algal metabolites; Antibacterial activity; Freshwater; Marine; Multidrug resistant (MDR)
Autoři
BHOWMICK, S.; MAZUMDAR, A.; MOULICK, A.; ADAM, V.
Vydáno
30. 11. 2020
ISSN
0734-9750
Periodikum
BIOTECHNOLOGY ADVANCES
Ročník
43
Číslo
107571
Stát
Spojené království Velké Británie a Severního Irska
Strany od
1
Strany do
18
Strany počet
URL
https://doi.org/10.1016/j.biotechadv.2020.107571
BibTex
@article{BUT165522, author="Sukanya {Bhowmick} and Aninda {Mazumdar} and Amitava {Moulick} and Vojtěch {Adam}", title="Algal Metabolites: An Inevitable Substitute for Antibiotics", journal="BIOTECHNOLOGY ADVANCES", year="2020", volume="43", number="107571", pages="1--18", doi="10.1016/j.biotechadv.2020.107571", issn="0734-9750", url="https://doi.org/10.1016/j.biotechadv.2020.107571" }