Přístupnostní navigace
E-přihláška
Vyhledávání Vyhledat Zavřít
Detail publikace
SKOPALÍK, J. PRŮCHA, J. SEKORA, J. ČMIEL, V. PARAK, T. MASEK, j.
Originální název
TEST OF COMPLEX NANOSTRUCTURES AS GENE DELIVERY SYSTEM TO CARDIAC CELLS
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
angličtina
Originální abstrakt
Various nanostructures, including liposomes, dendrimers, polymers, carbon or silicon materials, and metal nanoparticles seems to be evaluated as carriers in different gene delivery systems. Muscle cells are target of modern gene medicine, due to of the much pathology (arrhythmias, channels pathological mutation, abnormal apoptosis) with limited curability by traditional drugs. The zeta potential of the muscle cells were identified by non-traditional method of DLS. This was starting point to setting of parameters for experimental liposome, the liposome surface charge have been tested and modified by cationic plasmid and final complex was evaluated as delivery system of DNA into the muscle cardiac cells.
Klíčová slova
Nanoliposom; nanoparticle; transfection; zeta potential; cell engineering; regenerative medicine
Autoři
SKOPALÍK, J.; PRŮCHA, J.; SEKORA, J.; ČMIEL, V.; PARAK, T.; MASEK, j.
Vydáno
28. 12. 2020
Nakladatel
TANGER LTD
Místo
SLEZSKA
ISBN
978-80-87294-98-7
Kniha
NANOCON
Strany od
342
Strany do
346
Strany počet
5
BibTex
@inproceedings{BUT166063, author="SKOPALÍK, J. and PRŮCHA, J. and SEKORA, J. and ČMIEL, V. and PARAK, T. and MASEK, j.", title="TEST OF COMPLEX NANOSTRUCTURES AS GENE DELIVERY SYSTEM TO CARDIAC CELLS", booktitle="NANOCON", year="2020", pages="342--346", publisher="TANGER LTD", address="SLEZSKA", doi="10.37904/nanocon.2020.3757", isbn="978-80-87294-98-7" }