Detail publikace

Questions about the role of P3HT nanoparticles in retinal stimulation

PALANKER, D. GLOWACKI, E. GHEZZI, D.

Originální název

Questions about the role of P3HT nanoparticles in retinal stimulation

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Maya-Vetencourt et al.1 recently reported that poly[3-hexylthiophene] nanoparticles (P3HT NPs) injected in the subretinal space of the rat model of retinal dystrophy (the Royal College of Surgeons (RCS) model)) “mediate light-evoked stimulation of retinal neurons and persistently rescue visual function”. The article also reported that the light-evoked stimulation of retinal neurons is electrical in nature and is mediated by a capacitive coupling between the NPs and the cell membrane. To support these claims, the authors performed a series of experiments that demonstrated the P3HT NPs induced a cellular response in vitro, a retinal response ex vivo and rescue the visual functions in vivo. However, a number of inconsistencies throughout the article cast doubt on these results and their interpretation, as outlined below.

Klíčová slova

P3HT nanoparticles; retinal stimulation

Autoři

PALANKER, D.; GLOWACKI, E.; GHEZZI, D.

Vydáno

23. 12. 2021

Nakladatel

NATURE PORTFOLIO

Místo

BERLIN

ISSN

1748-3395

Periodikum

Nature Nanotechnology (electronic)

Ročník

16

Číslo

12

Stát

Spojené státy americké

Strany od

1330

Strany do

1332

Strany počet

3

URL

https://www.nature.com/articles/s41565-021-01044-6

BibTex

@article{BUT176436,
  author="Daniel {Palanker} and Eric Daniel {Glowacki} and Diego {Ghezzi}",
  title="Questions about the role of P3HT nanoparticles in retinal stimulation",
  journal="Nature Nanotechnology (electronic)",
  year="2021",
  volume="16",
  number="12",
  pages="1330--1332",
  doi="10.1038/s41565-021-01044-6",
  issn="1748-3395",
  url="https://www.nature.com/articles/s41565-021-01044-6"
}