Detail publikace

Clinical presentation and pulmonary function tests in post-acute COVID-19 patients

Genzor, S. Jakubec, P Sova, M. Mizera, J. Joppa, P. Burget, R. Pobeha, P.

Originální název

Clinical presentation and pulmonary function tests in post-acute COVID-19 patients

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Aims. The study analysed post-acute COVID-19 symptoms and the pulmonary function test (PFT) results in patients surviving the native strain of the virus. Methods. The study was prospective; the inclusion criteria were positive PCR test for SARS-CoV-2 and age 18-100. Exclusion criteria were active respiratory infection, known or suspicious pre-existing pulmonary disease, cardiac failure,recent or acute pulmonary embolism, anaemia, and neuromuscular diseases. The recruitment period was 1st March 2020 – 25th December 2020. The initial examination was performed 4–12 weeks after the disease onset. All subjects underwent physical examination, anamnesis, chest x-ray and PFT. Results. The study involved 785 subjects (345 male) mean age 53.8 (SD 14.6). The disease severity groups were: mild (G1), moderate (G2) and severe/critical (G3). Anosmia was present in the acute disease phase in 45.2% of G1 patients, but only in 4.5% of G3 patients. Dyspnoea occurred frequently in more severe groups (40%, 51.8% and 63.7% for G1, G2 and G3 respectively), while cough and fatigue showed no relationship to disease severity. Females were more likely to experience persistent symptoms. PFT results were significantly decreased in more severe groups compared to the mild COVID-19 patients, diffusing capacity was 86.3%, 79% and 68% of predicted values in G1, G2 and G3 respectively. Conclusion. Anosmia during the acute phase was associated with mild disease, persisting dyspnoea was more frequent after more severe COVID-19. Females tended to have persisting symptoms in post-acute phase more frequently. PFT results showed decrease with disease severity.

Klíčová slova

covid

Autoři

Genzor, S.; Jakubec, P; Sova, M.; Mizera, J.; Joppa, P.; Burget, R.; Pobeha, P.

Vydáno

8. 9. 2022

Nakladatel

PALACKY UNIVERSITY

Místo

Czech Republic

ISSN

1804-7521

Periodikum

BIOMEDICAL PAPERS-OLOMOUC

Ročník

166

Číslo

XX

Stát

Česká republika

Strany od

1

Strany do

7

Strany počet

7

URL

https://pubmed.ncbi.nlm.nih.gov/36128850/

BibTex

@article{BUT179091,
  author="Genzor, S. and Jakubec, P and Sova, M. and Mizera, J. and Joppa, P. and Burget, R. and Pobeha, P.",
  title="Clinical presentation and pulmonary function tests in post-acute COVID-19 patients",
  journal="BIOMEDICAL PAPERS-OLOMOUC",
  year="2022",
  volume="166",
  number="XX",
  pages="1--7",
  doi="10.5507/bp.2022.039",
  issn="1804-7521",
  url="https://pubmed.ncbi.nlm.nih.gov/36128850/"
}