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SCHWARZEROVÁ, J. ČEJKOVÁ, D.
Originální název
Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
angličtina
Originální abstrakt
Tracing horizontal gene flux across strains in farm animals is one of the important steps for research focused on detection and genomic enzymology of genes conferring antibiotic resistance. In this study, we have built the comprehensive computational methodology for the detection of horizontal genes transfer elements via pan-genome analysis. In total, 133 anaerobes isolated from chicken gastrointestinal tract were examined for the presence of traits of horizontal transfer. The shared genes from all isolates, so called core genome genes were identified and characterised in order to assign the function to the gene within individual bacterial cell and within community of cells. This study provides an evidence that horizontal transmission frequently occurs not only between closely related bacteria, but also between distant taxonomical groups. Hence chickens are known primary reservoirs of antibiotic resistance genes, and the dissemination of these genes to other bacterial pathogens often leads to life-threatening infections, even within human population. Thus, the research on this subject, and the associated results are of a great importance for public health.
Klíčová slova
Comparative Genomics, Core Genome, Antibiotics Resistance, Chicken Microbiome
Autoři
SCHWARZEROVÁ, J.; ČEJKOVÁ, D.
Vydáno
26. 4. 2022
Nakladatel
Brno University of Technology, Faculty of Electrical Engineering and Communication
Místo
Brno
ISBN
978-80-214-6029-4
Kniha
Proceedings I of the 28th Conference STUDENT EEICT 2022 General Papers
Číslo edice
1
Strany od
416
Strany do
420
Strany počet
5
URL
https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2022_sbornik_1_v2.pdf
BibTex
@inproceedings{BUT179426, author="Jana {Schwarzerová} and Darina {Čejková}", title="Identification of horizontal genes transfer elements across strains inhabiting the same niche using pan-genome analysis", booktitle="Proceedings I of the 28th Conference STUDENT EEICT 2022 General Papers", year="2022", number="1", pages="416--420", publisher="Brno University of Technology, Faculty of Electrical Engineering and Communication", address="Brno", isbn="978-80-214-6029-4", url="https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2022_sbornik_1_v2.pdf" }