Přístupnostní navigace
E-přihláška
Vyhledávání Vyhledat Zavřít
Detail publikace
VYSOKÁ, M. SZOTKOWSKI, M. SLANINOVÁ, E. DZURICKÁ, L. STREČANSKÁ, P. BLAŽKOVÁ, J. MÁROVÁ, I.
Originální název
Oleaginous Yeast Extracts and Their Possible Effects on Human Health.
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Four non-conventional oleaginous and pigmented yeast strains of Metschnikowia pulcherrima, Cystofilobasidium infirmominiatum, Phaffia rhodozyma, and Rhodotorula kratochvilovae were used in this study. Complex yeast extracts were prepared and tested for biological activity, safety, and effect on human health. In this paper, we measured the antioxidant activity and antimicrobial effect of yeast biomass as a whole and their extracts to compare the influence of carotenoids and other bioactive substances in the studied biomass. All yeast extracts exhibited a significant dose-dependent antimicrobial effect against both G+ and G- bacteria and had a strong antioxidant effect. No cytotoxicity in the mouse melanoma B16F1 cell line was found in concentrations up to 20% of rehydrated biomass in cell medium. All of the extracts were cytotoxic at a concentration of 5 mg of extract/g of dry biomass. All the pigmented yeast extracts showed some positive results for apoptosis of murine melanoma cell lines and are therefore strong candidates positively effect human health. Red yeast cell biomass is a prospective material with many attractive biological functions and can be used in the food industry, as a pharmaceutical material, or in the feed industry.
Klíčová slova
oleaginous yeast; pigmented yeasts; bioactive compounds; antimicrobial effect; cytotoxic effect; apoptosis
Autoři
VYSOKÁ, M.; SZOTKOWSKI, M.; SLANINOVÁ, E.; DZURICKÁ, L.; STREČANSKÁ, P.; BLAŽKOVÁ, J.; MÁROVÁ, I.
Vydáno
16. 2. 2023
Nakladatel
MDPI
ISSN
2076-2607
Periodikum
Microorganisms
Ročník
11
Číslo
2
Stát
Švýcarská konfederace
Strany od
1
Strany do
13
Strany počet
URL
https://www.mdpi.com/2076-2607/11/2/492
Plný text v Digitální knihovně
http://hdl.handle.net/11012/213541
BibTex
@article{BUT183470, author="Marie {Vysoká} and Martin {Szotkowski} and Eva {Slaninová} and Lucia {Dzurická} and Paulína {Strečanská} and Jana {Blažková} and Ivana {Márová}", title="Oleaginous Yeast Extracts and Their Possible Effects on Human Health.", journal="Microorganisms", year="2023", volume="11", number="2", pages="1--13", doi="10.3390/microorganisms11020492", issn="2076-2607", url="https://www.mdpi.com/2076-2607/11/2/492" }