Detail publikace

Molecular Design of FR/NIR Emitting Materials for Bioimaging and Utilization of Host-Guest Interactions as a Way of Increasing Fluorescence Intensity

SMOLKA, R. KOLAŘÍKOVÁ, A. LUŇÁK, S. VALA, M. IMRAMOVSKÝ, A. PAUK, K.

Originální název

Molecular Design of FR/NIR Emitting Materials for Bioimaging and Utilization of Host-Guest Interactions as a Way of Increasing Fluorescence Intensity

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

The intense solid-state fluorescence (SSF) is desirable for light-emitting field-effect transistors, organic light- emitting diodes (OLEDs), or water-dispersible nanoparticles for bioimaging. In this study, emphasis will be placed on the characterization of photoluminescence materials and their potential use as nanoparticles for in vivo bioimaging. By utilizing FR/NIR emitting materials, fluorescence imaging benefits from decreased self-fluorescence and the reduction of light scattering. In this study, to obtain NIR fluorescence, an intramolecular electronic transition of charge-transfer (CT) character is utilized. Unfortunately, such systems result in narrow band-gap organic materials and inevitably lead to reduced solid-state fluorescence quantum yields due to the promotion of intramolecular non-radiative processes. To overcome this, reduction of exciton migration via self-trapping is pursued. Crystal engineering methods are used to achieve either excimer-type NIR fluorescence or utilize so-called host-guest systems (HG), in which the effect of resonance energy transfer increases the solid-state fluorescence quantum yield of a fluorophore beyond its usual level. Such systems are deployed in the form of nanoparticles, showing increased QY of new π-conjugated fluorescent molecules based on derivates of DPA-DPS-EWG, such as DPA-DPS-IOO from 5 % to 14 % at 693 nm. This demonstrates the potential of such an approach as a way of obtaining nanoparticles with increased fluorescence intensity in the FR/NIR region, which is desirable for their application in NIR bioimaging.

Klíčová slova

FR/NIR fluorescence, nanoparticles, host-guest mixtures, charge-transfer electronic transitions, bioimaging

Autoři

SMOLKA, R.; KOLAŘÍKOVÁ, A.; LUŇÁK, S.; VALA, M.; IMRAMOVSKÝ, A.; PAUK, K.

Vydáno

27. 8. 2023

Strany od

572

Strany do

573

Strany počet

2

BibTex

@misc{BUT185027,
  author="Rastislav {Smolka} and Adéla {Kolaříková} and Karel {Pauk} and Stanislav {Luňák} and Aleš {Imramovský} and Martin {Vala}",
  title="Molecular Design of FR/NIR Emitting Materials for Bioimaging and Utilization of Host-Guest Interactions as a Way of Increasing Fluorescence Intensity",
  year="2023",
  pages="572--573",
  note="abstract"
}