Detail publikace

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

SCHWARZEROVÁ, J. LABANAVA, A. RYCHLÍK, I. VARGA, M. ČEJKOVÁ, D.

Originální název

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

The horizontal transfer of mobile gene elements between bacteria plays a crucial role in their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of genes conferring antibiotic and heavy-metal resistance, and thus contributes to the worldwide emergence and spread of drug-resistance pathogens. This process is instrumental in maintaining genetic diversity within bacterial populations and facilitates their adaptation to novel environments. It allows bacteria to acquire genes responsible for the synthesis of enzymes that utilize alternative energy sources and substrates. Furthermore, bacteria can acquire genes associated with toxin production and increased virulence. Horizontal gene transfer serves as a pivotal mechanism in bacterial evolution, enabling the acquisition of novel genetic information and enhancing their capabilities. However, the proper detection and identification of horizontally transferred genes at the microbiome scale is challenging, whether using wet-lab experime

Klíčová slova

horizontal gene transfer, bacterial genomics, mobilome, microbiome, genome analysis

Autoři

SCHWARZEROVÁ, J.; LABANAVA, A.; RYCHLÍK, I.; VARGA, M.; ČEJKOVÁ, D.

Vydáno

11. 10. 2023

Nakladatel

Frontiers

ISSN

2813-6144

Periodikum

Frontiers in Bacteriology

Ročník

2

Číslo

1

Stát

Spojené státy americké

Strany počet

8

URL

https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full

Plný text v Digitální knihovně

http://hdl.handle.net/11012/245103

BibTex

@article{BUT185424,
  author="Jana {Schwarzerová} and Anastasiya {Labanava} and Ivan {Rychlík} and Margaret {Varga} and Darina {Čejková}",
  title="A minireview on the bioinformatics analysis of mobile gene elements in microbiome research",
  journal="Frontiers in Bacteriology",
  year="2023",
  volume="2",
  number="1",
  pages="8",
  doi="10.3389/fbrio.2023.1275910",
  issn="2813-6144",
  url="https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full"
}