Detail publikace

Evaluation of Fractional Calculus and Delta Parameters in Prodromal Diagnosis of Dementia with Lewy Bodies utilizing Online Handwriting

MUCHA, J. GAVENČIAK, M. MEKYSKA, J. FAÚNDEZ ZANUY, M. BRABENEC, L. REKTOROVÁ, I.

Originální název

Evaluation of Fractional Calculus and Delta Parameters in Prodromal Diagnosis of Dementia with Lewy Bodies utilizing Online Handwriting

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

This study evaluates the effect of fractional order derivatives (FD) and delta parameters in the prodromal diagnosis of dementia with Lewy bodies (DLB) utilizing online handwriting analysis. With DLB being the second most prevalent neurodegenerative dementia, early detection is critical for timely intervention. Leveraging advanced mathematical models, we explored the potential of FD-based and delta-based kinematic handwriting features compared to baseline. The analysis included 45 participants at high risk of developing DLB and 29 healthy controls who performed the Archimedean spiral task. Our findings reveal that FD-based kinematic features, mainly derived from the horizontal velocity at low alpha levels, are significantly discriminative. Moreover, the binary classification model trained with FD-based features achieved a balanced accuracy BACC=0.75. The study emphasizes the relevance of advanced kinematic parametrization in neurodegenerative disease diagnostics, presenting novel features as promising tools for DLB screening.

Klíčová slova

biomedical signal processing, feature extraction, fractional calculus, delta parameters, dementia with Lewy bodies, online handwriting, prodromal diagnosis

Autoři

MUCHA, J.; GAVENČIAK, M.; MEKYSKA, J.; FAÚNDEZ ZANUY, M.; BRABENEC, L.; REKTOROVÁ, I.

Vydáno

26. 8. 2024

Nakladatel

EURASIP

Místo

Lyon, France

ISBN

978-9-4645-9361-7

Kniha

2024 32nd European Signal Processing Conference (EUSIPCO)

Edice

32

Strany od

1731

Strany do

1735

Strany počet

5

URL

https://ieeexplore.ieee.org/document/10715381

BibTex

@inproceedings{BUT189458,
  author="Ján {Mucha} and Michal {Gavenčiak} and Jiří {Mekyska} and Marcos {Faúndez Zanuy} and Luboš {Brabenec} and Irena {Rektorová}",
  title="Evaluation of Fractional Calculus and Delta Parameters in Prodromal Diagnosis of Dementia with Lewy Bodies utilizing Online Handwriting",
  booktitle="2024 32nd European Signal Processing Conference (EUSIPCO)",
  year="2024",
  series="32",
  pages="1731--1735",
  publisher="EURASIP",
  address="Lyon, France",
  doi="10.23919/EUSIPCO63174.2024.10715381",
  isbn="978-9-4645-9361-7",
  url="https://ieeexplore.ieee.org/document/10715381"
}