Detail publikace

Comprehensive characterization of natural polysaccharide-based hydrogels with gradient structure in concentration and stiffness

ZINKOVSKA, N. TRUDIČOVÁ, M. MARKOVÁ, K. PEKAŘ, M. SMILEK, J.

Originální název

Comprehensive characterization of natural polysaccharide-based hydrogels with gradient structure in concentration and stiffness

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Gradient hydrogels are functionally graded biomaterials that over the last decades have garnered significant attention as valuable materials for tissue repair and regeneration. This study elucidates key factors crucially determining the character or pattern of a buoyancy-driven gradient in agarose hydrogels and also provides fundamental information regarding the complex interpretation of the formed gradient hydrogels obtained by the different characterization techniques, including rheology, UV-Vis spectroscopy, FCS, AFM, SEM. The employed techniques were successfully optimized to enhance the understanding of the gradient properties of these hydrogels. Demonstrated results showed that the agarose concentration gradient could be successfully controlled and tailored, which offers a valuable contribution to the design of gradient hydrogel. Moreover, a novel method for determining the average agarose concentration along the gradient axis is presented, improving the precision of gradient characterization. The integration of these approaches significantly enhances the comprehension of the internal structure and properties of gradient materials, contributing to advancements in their understanding and application.

Klíčová slova

Hydrogels, Stiffness gradient, Rheology, Atomic force microscopy, Fluorescence correlation spectroscopy, Polysaccharides

Autoři

ZINKOVSKA, N.; TRUDIČOVÁ, M.; MARKOVÁ, K.; PEKAŘ, M.; SMILEK, J.

Vydáno

27. 9. 2024

Nakladatel

ELSEVIER

Místo

Amsterdam

ISSN

0927-7757

Periodikum

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Ročník

704

Číslo

135455

Stát

Nizozemsko

Strany počet

13

URL

https://www.sciencedirect.com/science/article/abs/pii/S0927775724023197

BibTex

@article{BUT190023,
  author="Natalia {Zinkovska} and Monika {Trudičová} and Kateřina {Marková} and Miloslav {Pekař} and Jiří {Smilek}",
  title="Comprehensive characterization of natural polysaccharide-based hydrogels with gradient structure in concentration and stiffness",
  journal="Colloids and Surfaces A: Physicochemical and Engineering Aspects",
  year="2024",
  volume="704",
  number="135455",
  pages="13",
  doi="10.1016/j.colsurfa.2024.135455",
  issn="0927-7757",
  url="https://www.sciencedirect.com/science/article/abs/pii/S0927775724023197"
}