Detail publikace

Microfluidics chips fabrication techniques comparison

LIU, X. SUN, A. BRODSKÝ, J. GABLECH, I. LEDNICKÝ, T VOPAŘILOVÁ, P. ZÍTKA, O. ZENG, W. NEUŽIL, P.

Originální název

Microfluidics chips fabrication techniques comparison

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This study investigates various microfluidic chip fabrication techniques, highlighting their applicability and limitations in the context of urgent diagnostic needs showcased by the COVID-19 pandemic. Through a detailed examination of methods such as computer numerical control milling of a polymethyl methacrylate, soft lithography for polydimethylsiloxane-based devices, xurography for glass-glass chips, and micromachining-based silicon-glass chips, we analyze each technique's strengths and trade-offs. Hence, we discuss the fabrication complexity and chip thermal properties, such as heating and cooling rates, which are essential features of chip utilization for a polymerase chain reaction. Our comparative analysis reveals critical insights into material challenges, design flexibility, and cost-efficiency, aiming to guide the development of robust and reliable microfluidic devices for healthcare and research. This work underscores the importance of selecting appropriate fabrication methods to optimize device functionality, durability, and production efficiency.

Klíčová slova

Microfluidics; Fabrication techniques; Thermal properties

Autoři

LIU, X.; SUN, A.; BRODSKÝ, J.; GABLECH, I.; LEDNICKÝ, T; VOPAŘILOVÁ, P.; ZÍTKA, O.; ZENG, W.; NEUŽIL, P.

Vydáno

20. 11. 2024

Nakladatel

NATURE PORTFOLIO

Místo

ENGLAND

ISSN

2045-2322

Periodikum

Scientific Reports

Ročník

14

Číslo

1

Stát

Spojené království Velké Británie a Severního Irska

Strany od

1

Strany do

13

Strany počet

13

URL

https://www.nature.com/articles/s41598-024-80332-2

Plný text v Digitální knihovně

http://hdl.handle.net/11012/250052

BibTex

@article{BUT193659,
  author="Xiaocheng {Liu} and Antao {Sun} and Jan {Brodský} and Imrich {Gablech} and Tomáš {Lednický} and Petra {Vopařilová} and Ondřej {Zítka} and Wen {Zeng} and Pavel {Neužil}",
  title="Microfluidics chips fabrication techniques comparison",
  journal="Scientific Reports",
  year="2024",
  volume="14",
  number="1",
  pages="13",
  doi="10.1038/s41598-024-80332-2",
  issn="2045-2322",
  url="https://www.nature.com/articles/s41598-024-80332-2"
}