Detail publikace

A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection

ZÍTKA, O. ŠKUTKOVÁ, H. ADAM, V. TRNKOVÁ, L. BABULA, P. HUBÁLEK, J. PROVAZNÍK, I. KIZEK, R.

Originální název

A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

We studied the electrochemical behaviour of adenine derivates (adenosine, 2 - aminopurine, 2,6 - diaminopurine,6 - benzyl - aminopurine, adenosine - monophosphate, cyclic adenosine monophosphate, nicotin amide adenine dinucleotide, adenosine - triphosphate, S-adenosyl - l - methionine and synthetic derivatives AD -3, AD - 6 and AD-9) using flow injection analysis with electrochemical detection. The influences of pH, flow rate and potential on the signal height of the studied derivates were tested. The optimal pH was 3, the flow rate of the mobile phase 0.75 mL min 1 and the potential 1100 mV. Further, we attempted to characterize each of the studied derivatives by mathematical equations and classic analytical parameters.The lowest detecti on limit was estimated for adenine as 0.9 nM and 2 - amino - purine as 0.5nM

Klíčová slova

Adenine derivatives, Flow injection analysis, Amperometric detection, Glassy carbon electrode, Electroactivity

Autoři

ZÍTKA, O.; ŠKUTKOVÁ, H.; ADAM, V.; TRNKOVÁ, L.; BABULA, P.; HUBÁLEK, J.; PROVAZNÍK, I.; KIZEK, R.

Rok RIV

2011

Vydáno

21. 6. 2011

Nakladatel

WILEY

Místo

Weinheim

ISSN

1040-0397

Periodikum

ELECTROANALYSIS

Ročník

23

Číslo

7

Stát

Spolková republika Německo

Strany od

1556

Strany do

1567

Strany počet

12

BibTex

@article{BUT50938,
  author="Ondřej {Zítka} and Helena {Vítková} and Vojtěch {Adam} and Libuše {Trnková} and Petr {Babula} and Jaromír {Hubálek} and Valentine {Provazník} and René {Kizek}",
  title="A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection",
  journal="ELECTROANALYSIS",
  year="2011",
  volume="23",
  number="7",
  pages="1556--1567",
  doi="10.1002/elan.201100064",
  issn="1040-0397"
}