Detail publikace

Utilisation of solid phase extraction method for determination of drug residues in the river water

ŽENATOVÁ, P. VÁVROVÁ, M.

Originální název

Utilisation of solid phase extraction method for determination of drug residues in the river water

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

This study examines different solid phase extraction (SPE) methods for preconcentration and purification of antibiotics in the river water. Drugs and their residues enter to the wastewater treatment plants (WWTP) within excrements. It is known, that here they are not completely removed and can discharge to the environment. Their further negative impact on the water and soil ecosystem cannot therefore be excluded. Sulfonamides, which are widely used in human and veterinary medicine, were selected as target compounds. Recoveries of the selected antibiotics at different sample volumes on various SPE columns were tested. Two SPE columns with different amount of sorbent were chosen (ENVI 18 SPE Tubes, 6 ml, 0,5 g and ENVI 18 SPE Tubes, 6 ml, 1 g); one sample without pH adjustment, and one sample with pH adjustment. Seven different volumes (10, 50, 100, 200, 300, 400; 500 ml) were tested. For determination of sulfonamides high performance liquid chromatography with diode array detector was used.

Klíčová slova

drug residua, solid phase extraction, liquid chromatography

Autoři

ŽENATOVÁ, P.; VÁVROVÁ, M.

Vydáno

24. 9. 2011

Nakladatel

16th International Symposium on Environmental Pollution and its Impact in the Mediterranean Region

Místo

Ioannina

BibTex

@misc{BUT73777,
  author="Petra {Dvořáková} and Milada {Vávrová}",
  title="Utilisation of solid phase extraction method for determination of drug residues in the river water",
  year="2011",
  publisher="16th International Symposium on Environmental Pollution and its Impact in the Mediterranean Region",
  address="Ioannina",
  note="abstract"
}