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LÍZAL, F. JEDELSKÝ, J. ADAM, J. BĚLKA, M. JÍCHA, M.
Originální název
Application of Positron Emission Tomography to Aerosol Transport Research in a Model of Human Lungs
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
angličtina
Originální abstrakt
Positron Emission Tomography (PET) is a convenient method for measurement of aerosol deposition in complex models of lungs. It allows not only the evaluation of regional deposition characteristics but also precisely detects deposition hot spots. The method is based on a detection of a pair of annihilation photons moving in opposite directions as a result of positron – electron interaction after the positron emission decay of a suitable radioisotope. Liquid di(2-ethylhexyl) sebacate (DEHS) particles tagged with fluorine-18 as a radioactive tracer were generated by condensation monodisperse aerosol generator. Aerosol deposition was measured for three different inhalation flowrates and for two sizes of particles. Combination of PET with Computed Tomography (CT) in one device allowed precise localisation of particular segments of the model. The results proved correlation of deposition efficiency with Stokes number, which means that the main deposition mechanism is inertial impaction. As a next task the methodology for tagging the solid aerosol particles with radioactive tracer will be developed and deposition of porous and fiber aerosols will be measured.
Klíčová slova
aerosol transport, aerosol deposition, positron emission tomography, human lung model
Autoři
LÍZAL, F.; JEDELSKÝ, J.; ADAM, J.; BĚLKA, M.; JÍCHA, M.
Rok RIV
2012
Vydáno
9. 4. 2013
Nakladatel
EDP Sciences
Místo
Francie
ISBN
978-80-7372-912-7
Kniha
EPJ Web of Conferences
ISSN
2100-014X
Periodikum
Ročník
45
Číslo
1
Stát
Francouzská republika
Strany od
Strany do
4
Strany počet
URL
https://www.epj-conferences.org/articles/epjconf/abs/2013/06/epjconf_efm2013_01060/epjconf_efm2013_01060.html
Plný text v Digitální knihovně
http://hdl.handle.net/11012/193652
BibTex
@inproceedings{BUT95329, author="František {Lízal} and Jan {Jedelský} and Jan {Adam} and Miloslav {Bělka} and Miroslav {Jícha}", title="Application of Positron Emission Tomography to Aerosol Transport Research in a Model of Human Lungs", booktitle="EPJ Web of Conferences", year="2013", journal="EPJ Web of Conferences", volume="45", number="1", pages="1--4", publisher="EDP Sciences", address="Francie", doi="10.1051/epjconf/20134501060", isbn="978-80-7372-912-7", issn="2100-014X", url="https://www.epj-conferences.org/articles/epjconf/abs/2013/06/epjconf_efm2013_01060/epjconf_efm2013_01060.html" }