Detail publikace

Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs.

PEKAŘÍK, V. GUMULEC, J. MASAŘÍK, M. KIZEK, R. ADAM, V.

Originální název

Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs.

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

More surprising are the findings that levels of various miRNAs are well correlated with presence of specific tumours and formation of metastases. Moreover, these small regulatory molecules play a role in the resistance of cancer cells to commonly used anti-cancer drugs, such as cisplatin, anthracyclines, and taxanes. In that respect, miRNAs become very attractive target for potential therapeutic interventions

Klíčová slova

Prostate carcinoma, markers, miRNA, circulating miRNAs, metallothionein, anti-cancer drugs, platinum based cytostatics, zinc, resistance, metastases.

Autoři

PEKAŘÍK, V.; GUMULEC, J.; MASAŘÍK, M.; KIZEK, R.; ADAM, V.

Rok RIV

2013

Vydáno

1. 1. 2013

ISSN

0929-8673

Periodikum

CURRENT MEDICINAL CHEMISTRY

Ročník

20

Číslo

4

Stát

Stát Spojené arabské emiráty

Strany od

534

Strany do

544

Strany počet

11

BibTex

@article{BUT98895,
  author="Vladimír {Pekařík} and Jaromír {Gumulec} and Michal {Masařík} and René {Kizek} and Vojtěch {Adam}",
  title="Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs.",
  journal="CURRENT MEDICINAL CHEMISTRY",
  year="2013",
  volume="20",
  number="4",
  pages="534--544",
  issn="0929-8673"
}