Detail publikace

Hydrogels based on cationic polyelectrolytes

JARÁBKOVÁ, S. MRAVEC, F. SMILEK, J. PEKAŘ, M.

Originální název

Hydrogels based on cationic polyelectrolytes

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

The main aim of this work is laboratory preparation and characterization of hydrogels based on cationic polyelectrolytes. Cationic polyelectrolytes can interact with oppositely charged surfactants via electrostatic forces. Interactions between cationic polyelectrolytes and anionic surfactants can generate physical gels (under proper conditions such as temperature, pH, ionic strenght) and surfactants are able to form micellar structures suitable for solubilizing hydrophobic compounds in aqueous environment of the gel. Resulting materials are hydrogels which contain hydrophobic nanodomains so it is possible to use like porters in drug delivery in medicine, e.g. hydrophobic drugs for topical applications (wound healing and so on). The presence of hydrophobic nanodomains was tested by solubilization tests with the help of hydrophobic dyes (e.g. Oil red O, prodan). Mechanical properties of prepared materials were tested rheologically (in dependence of their composition). This work is focused on the preparation of gels from positively charged polysaccharides dextran hydrochloride and negatively charged surfactant sodium dodecyl sulphate.

Klíčová slova

hydrogel, polyelectrolyte, surfactant, nanodomain, micelles, rheology, solubilization test

Autoři

JARÁBKOVÁ, S.; MRAVEC, F.; SMILEK, J.; PEKAŘ, M.

Vydáno

23. 3. 2017

Nakladatel

Vysoké učení technické v Brně, Fakulta chemická

Místo

Brno

ISBN

978-80-214-5489-7

Kniha

Sborník příspěvků

Edice

1.

Číslo edice

první

Strany od

194

Strany do

197

Strany počet

4

BibTex

@inproceedings{BUT138705,
  author="Sabína {Jarábková} and Filip {Mravec} and Jiří {Smilek} and Miloslav {Pekař}",
  title="Hydrogels based on cationic polyelectrolytes",
  booktitle="Sborník příspěvků",
  year="2017",
  series="1.",
  number="první",
  pages="194--197",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  address="Brno",
  isbn="978-80-214-5489-7"
}