Detail publikace

Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach

HEGER, R. KADLEC, M. TRUDIČOVÁ, M. ZINKOVSKA, N. HAJZLER, J. PEKAŘ, M. SMILEK, J.

Originální název

Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Nowadays, hydrogels are found in many applications ranging from the industrial to the biological (e.g., tissue engineering, drug delivery systems, cosmetics, water treatment, and many more). According to the specific needs of individual applications, it is necessary to be able to modify the properties of hydrogel materials, particularly the transport and mechanical properties related to their structure, which are crucial for the potential use of the hydrogels in modern material engineering. Therefore, the possibility of preparing hydrogel materials with tunable properties is a very real topic and is still being researched. A simple way to modify these properties is to alter the internal structure by adding another component. The addition of natural substances is convenient due to their biocompatibility and the possibility of biodegradation. Therefore, this work focused on hydrogels modified by a substance that is naturally found in the tissues of our body, namely lecithin. Hydrogels were prepared by different types of crosslinking (physical, ionic, and chemical). Their mechanical properties were monitored and these investigations were supplemented by drying and rehydration measurements, and supported by the morphological characterization of xerogels. With the addition of natural lecithin, it is possible to modify crucial properties of hydrogels such as porosity and mechanical properties, which will play a role in the final applications.

Klíčová slova

lecithin; hydrogel; rheology; scanning electron microscopy; drying and swelling; extracellular matrix; mesh size

Autoři

HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; HAJZLER, J.; PEKAŘ, M.; SMILEK, J.

Vydáno

13. 2. 2022

Nakladatel

MDPI

Místo

Basel, Switzerland

ISSN

2310-2861

Periodikum

Gels

Ročník

8

Číslo

2

Stát

Švýcarská konfederace

Strany od

1

Strany do

23

Strany počet

23

URL

https://www.mdpi.com/2310-2861/8/2/115

Plný text v Digitální knihovně

http://hdl.handle.net/11012/203935

BibTex

@article{BUT176575,
  author="Richard {Heger} and Martin {Kadlec} and Monika {Trudičová} and Natalia {Zinkovska} and Jan {Hajzler} and Miloslav {Pekař} and Jiří {Smilek}",
  title="Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach",
  journal="Gels",
  year="2022",
  volume="8",
  number="2",
  pages="1--23",
  doi="10.3390/gels8020115",
  issn="2310-2861",
  url="https://www.mdpi.com/2310-2861/8/2/115"
}