Detail publikace

Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line

CERNEI, N. ZÍTKA, O. SKALIČKOVÁ, S. GUMULEC, J. SZTALMACHOVÁ, M. MERLOS RODRIGO, M. SOCHOR, J. MASAŘÍK, M. ADAM, V. HUBÁLEK, J. TRNKOVÁ, L. KRUSEOVÁ, J. ECKSCHLAGER, T. KIZEK, R.

Originální název

Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Sarcosine is currently one of the most discussed markers of prostate cancer. It is involved in amino acid metabolism and methylation processes that occur during the progression of prostate cancer. In this study, we monitored the effect of the addition of sarcosine (0; 10; 250; 500; 1,000 and 1,500 uM) in a time-dependent manner (0-72 h) on the PC-3 prostate cancer cell line. For the assessment of cell viability, the commonly used MTT test was employed. Furthermore, ion-exchange liquid chromatography was used for the determination of sarcosine content in the PC-3 cells

Klíčová slova

sarcosine, prostate cancer, metallothionein, antioxidant activity, chip electrophoresis, ion-exchange chromatography, Brdicka reaction

Autoři

CERNEI, N.; ZÍTKA, O.; SKALIČKOVÁ, S.; GUMULEC, J.; SZTALMACHOVÁ, M.; MERLOS RODRIGO, M.; SOCHOR, J.; MASAŘÍK, M.; ADAM, V.; HUBÁLEK, J.; TRNKOVÁ, L.; KRUSEOVÁ, J.; ECKSCHLAGER, T.; KIZEK, R.

Rok RIV

2013

Vydáno

1. 6. 2013

ISSN

1021-335X

Periodikum

ONCOLOGY REPORTS

Ročník

29

Číslo

6

Stát

Řecká republika

Strany od

2459

Strany do

2466

Strany počet

8

BibTex

@article{BUT100725,
  author="Natalia Vladimirovna {Cernei} and Ondřej {Zítka} and Sylvie {Skaličková} and Jaromír {Gumulec} and Markéta {Sztalmachová} and Miguel Ángel {Merlos Rodrigo} and Jiří {Sochor} and Michal {Masařík} and Vojtěch {Adam} and Jaromír {Hubálek} and Libuše {Trnková} and Jarmila {Kruseová} and Tomáš {Eckschlager} and René {Kizek}",
  title="Effect of sarcosine on antioxidant parameters and metallothionein content in the PC-3 prostate cancer cell line",
  journal="ONCOLOGY REPORTS",
  year="2013",
  volume="29",
  number="6",
  pages="2459--2466",
  doi="10.3892/or.2013.2389",
  issn="1021-335X"
}