Detail publikace

Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics

VACULOVIČOVÁ, M. ŠMERKOVÁ, K. PEKÁRKOVÁ, J. HUBÁLEK, J. ADAM, V. KIZEK, R.

Originální název

Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Cisplatin, carboplatin, and oxaliplatin represent three generations of platinum based drugs applied successfully for cancer treatment. As a consequence of the employment of platinum based cytostatics in the cancer treatment, it became necessary to study the mechanism of their action. Current accepted opinion is the formation of Pt-DNA adducts, but the mechanism of their formation is still unclear. Nanomaterials, as a progressively developing branch, can offer a tool for studying the interactions of these drugs with DNA

Klíčová slova

Capillary electrophoresis, DNA, Gel electrophoresis, Platinum cytostatic drugs, Quantum dots

Autoři

VACULOVIČOVÁ, M.; ŠMERKOVÁ, K.; PEKÁRKOVÁ, J.; HUBÁLEK, J.; ADAM, V.; KIZEK, R.

Rok RIV

2013

Vydáno

1. 3. 2013

Nakladatel

Wiley

Místo

Německo

ISSN

0173-0835

Periodikum

Electrophoresis

Ročník

34

Číslo

6

Stát

Spolková republika Německo

Strany od

801

Strany do

808

Strany počet

8

BibTex

@article{BUT100726,
  author="Markéta {Vaculovičová} and Kristýna {Šmerková} and Jana {Pekárková} and Jaromír {Hubálek} and Vojtěch {Adam} and René {Kizek}",
  title="Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics",
  journal="Electrophoresis",
  year="2013",
  volume="34",
  number="6",
  pages="801--808",
  doi="10.1002/elps.201200664",
  issn="0173-0835"
}