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VACULOVIČOVÁ, M. ŠMERKOVÁ, K. PEKÁRKOVÁ, J. HUBÁLEK, J. ADAM, V. KIZEK, R.
Originální název
Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Cisplatin, carboplatin, and oxaliplatin represent three generations of platinum based drugs applied successfully for cancer treatment. As a consequence of the employment of platinum based cytostatics in the cancer treatment, it became necessary to study the mechanism of their action. Current accepted opinion is the formation of Pt-DNA adducts, but the mechanism of their formation is still unclear. Nanomaterials, as a progressively developing branch, can offer a tool for studying the interactions of these drugs with DNA
Klíčová slova
Capillary electrophoresis, DNA, Gel electrophoresis, Platinum cytostatic drugs, Quantum dots
Autoři
VACULOVIČOVÁ, M.; ŠMERKOVÁ, K.; PEKÁRKOVÁ, J.; HUBÁLEK, J.; ADAM, V.; KIZEK, R.
Rok RIV
2013
Vydáno
1. 3. 2013
Nakladatel
Wiley
Místo
Německo
ISSN
0173-0835
Periodikum
Electrophoresis
Ročník
34
Číslo
6
Stát
Spolková republika Německo
Strany od
801
Strany do
808
Strany počet
8
BibTex
@article{BUT100726, author="Markéta {Vaculovičová} and Kristýna {Šmerková} and Jana {Pekárková} and Jaromír {Hubálek} and Vojtěch {Adam} and René {Kizek}", title="Glutathione modified CdTe quantum dots as a label for studying DNA interactions with platinum based cytostatics", journal="Electrophoresis", year="2013", volume="34", number="6", pages="801--808", doi="10.1002/elps.201200664", issn="0173-0835" }