Detail publikace

Conjugation Bovine Serum Albumine with CdTe Quantum Dots

CHOMOUCKÁ, J. DRBOHLAVOVÁ, J. MAJZLÍKOVÁ, P. PRÁŠEK, J. PEKÁREK, J. HRDÝ, R. HUBÁLEK, J.

Originální název

Conjugation Bovine Serum Albumine with CdTe Quantum Dots

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

There is a growing interest in using semiconductor quantum dots (QDs) as optical labels for biosensing events. QDs have been linked with bio-recognition molecules such as proteins, peptides and nucleic acids, and have been successfully used in biological and medical fields such as immunoassay, DNA hybridization, cell imaging and potential photodynamic therapy. In this paper, the interaction between bovine serum albumin (BSA) and water soluble CdTe QDs modified with different ligands (3-mercaptoacetic acid, thioglycolic acid and glutathione) was studied using the fluorescence spectroscopy. It was found that the presence of QDs led to a strong quenching effect of BSA, which could be explained by a covalent interaction between the protein and the quencher, demonstrating the formation of QDs-BSA bioconjugates.

Klíčová slova

Quantum dots, conjugation, bovine serum albumin

Autoři

CHOMOUCKÁ, J.; DRBOHLAVOVÁ, J.; MAJZLÍKOVÁ, P.; PRÁŠEK, J.; PEKÁREK, J.; HRDÝ, R.; HUBÁLEK, J.

Vydáno

16. 10. 2013

Nakladatel

Tanger, Ltd.

Místo

Ostrava

ISBN

978-80-87294-47-5

Kniha

Conference Proceedings 5th International Conference NANOCON 2013

Edice

1

Číslo edice

1

ISSN

NEUVEDENO

Strany od

566

Strany do

571

Strany počet

6

BibTex

@inproceedings{BUT102875,
  author="Jana {Pekárková} and Jana {Drbohlavová} and Petra {Majzlíková} and Jan {Prášek} and Jan {Pekárek} and Radim {Hrdý} and Jaromír {Hubálek}",
  title="Conjugation Bovine Serum Albumine with CdTe Quantum Dots",
  booktitle="Conference Proceedings 5th International Conference NANOCON 2013",
  year="2013",
  series="1",
  number="1",
  pages="566--571",
  publisher="Tanger, Ltd.",
  address="Ostrava",
  isbn="978-80-87294-47-5"
}