Detail publikace

Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives

PŘICHYSTALOVÁ, H. ALMONASY, N. ABDEL-LATTIF, A. ABDEL-RAHMAN, R. FOUDA, M. VOJTOVÁ, L. KOBĚRA, L. SPOTZ, Z. BURGERT, L. JANČÁŘ, J.

Originální název

Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The present work aims to the development of innovative new derivatives of chitosan that can be used for medical applications. This innovation is based on the synthesis and characterization of chitosan-g-aminoanthracene derivatives. Thus, N-(anthracen-9-yl)-4,6- dichloro-[1,3,5]-triazin-2-amine (AT) reacted with chitosan by the following steps: At first, cyanuric chloride reacted with 9-aminoanthracene to obtain N-(anthracen-9-yl)-4,6-dichloro- 40 [1,3,5]-triazin-2-amine (AT), then the AT reacted with chitosan to obtain (CH -g-AT). The final product of CH-g-AT was separated, purified and re-crystallized by dioxan. The structure of the prepared chitosan derivatives was confirmed by FTIR-ATR, solid-NMR, TGA, X-RD, and DSC. The new chitosan derivatives showed fluorescence spectra in liquid and in solid state as well. CH-g-AT showed also high antibacterial activity against gram-negative species (Escherichia coli).

Klíčová slova

chitosan, antibacterial activity, fluorescent derivatives

Autoři

PŘICHYSTALOVÁ, H.; ALMONASY, N.; ABDEL-LATTIF, A.; ABDEL-RAHMAN, R.; FOUDA, M.; VOJTOVÁ, L.; KOBĚRA, L.; SPOTZ, Z.; BURGERT, L.; JANČÁŘ, J.

Rok RIV

2014

Vydáno

1. 4. 2014

ISSN

0141-8130

Periodikum

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ročník

65

Číslo

1

Stát

Nizozemsko

Strany od

234

Strany do

240

Strany počet

580

BibTex

@article{BUT105081,
  author="Hana {Přichystalová} and Numan {Almonasy} and Abdelmohsen Moustafa {Abdellatif} and Rasha M. {Abdel-Rahman} and Moustafa M.D. {Fouda} and Lucy {Vojtová} and Libor {Koběra} and Zdeněk {Spotz} and Ladislav {Burgert} and Josef {Jančář}",
  title="Synthesis, characterization and antibacterial activity of new fluorescent chitosan derivatives",
  journal="INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES",
  year="2014",
  volume="65",
  number="1",
  pages="234--240",
  doi="10.1016/j.ijbiomac.2014.01.050",
  issn="0141-8130"
}