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MEKYSKA, J. SMÉKAL, Z. GALÁŽ, Z. MŽOUREK, Z. REKTOROVÁ, I. FAÚNDEZ ZANUY, M. LOPEZ-DE-IPINA, K.
Originální název
Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
angličtina
Originální abstrakt
Up to 90 % of patients with Parkinson’s disease (PD) suffer from hypokinetic dysathria (HD) which is also manifested in the field of phonation. Clinical signs of HD like monoloudness, monopitch or hoarse voice are usually quantified by conventional clinical interpretable features (jitter, shimmer, harmonic-to-noise ratio, etc.). This paper provides large and robust insight into perceptual analysis of 5 Czech vowels of 84 PD patients and proves that despite the clinical inexplicability the perceptual features outperform the conventional ones, especially in terms of discrimination power (classification accuracy ACC=92 %, sensitivity SEN=93 %, specificity SPE=92 %) and partial correlation with clinical scores like UPDRS (Unified Parkinson’s disease rating scale), MMSE (Mini-mental state examination) or FOG (Freezing of gait questionnaire), where p < 0.0001.
Klíčová slova
Perceptual features, perceptual analysis, Parkinson’s disease, hypokinetic dysarthria, speech processing
Autoři
MEKYSKA, J.; SMÉKAL, Z.; GALÁŽ, Z.; MŽOUREK, Z.; REKTOROVÁ, I.; FAÚNDEZ ZANUY, M.; LOPEZ-DE-IPINA, K.
Vydáno
23. 1. 2016
Nakladatel
Springer International Publishing
Místo
Switzerland
ISBN
978-3-319-28107-0
Kniha
Recent Advances in Nonlinear Speech Processing
Strany od
83
Strany do
91
Strany počet
9
BibTex
@inproceedings{BUT123875, author="Jiří {Mekyska} and Zdeněk {Smékal} and Zoltán {Galáž} and Zdeněk {Mžourek} and Irena {Rektorová} and Marcos {Faúndez Zanuy} and Karmele {Lopez-de-Ipina}", title="Perceptual Features as Markers of Parkinson’s Disease: The Issue of Clinical Interpretability", booktitle="Recent Advances in Nonlinear Speech Processing", year="2016", pages="83--91", publisher="Springer International Publishing", address="Switzerland", doi="10.1007/978-3-319-28109-4\{_}9", isbn="978-3-319-28107-0" }