Detail publikace

Simulation of size-dependent aerosol deposition in a realistic model of the upper human airways

FREDERIX, E. KUCZAJ, A. NORDLUND, M. BĚLKA, M. LÍZAL, F. JEDELSKÝ, J. ELCNER, J. JÍCHA, M. GEURTS, B.

Originální název

Simulation of size-dependent aerosol deposition in a realistic model of the upper human airways

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

An Eulerian internally mixed aerosol model is used for predictions of deposition inside a realistic cast of the human upper airways. The model, formulated in the multi-species and compressible framework, is solved using the sectional discretization of the droplet size distribution function to accurately capture size-dependent aerosol dynamics such as droplet drift, gravitational settling and diffusion. These three mechanisms are implemented in a consistent way in the model, guaranteeing that the total droplet mass as given by the droplet size distribution is always equal to the total droplet mass due to the mass concentration fields. To validate the model, we simulate monodisperse glycerol aerosol deposition inside the lung cast, for which experimental data is available. Provided that an adequate computational mesh is used and an adequate boundary treatment for the inertial deposition velocity, excellent agreement is found with the experimental data. Finally, we study the size-dependent deposition inside the lung cast for a polydisperse aerosol with droplet sizes ranging from the nanometer scale to beyond the micrometer scale. The typical ‘V-shape’ deposition curve is recovered. The aim of this paper is to 1) provide an overview of the Eulerian aerosol dynamics model and method, to 2) validate this method in a relevant complex lung geometry and to 3) explore the capabilities of the method by simulating polydisperse aerosol deposition.

Klíčová slova

aerosol deposition, respiratory airways

Autoři

FREDERIX, E.; KUCZAJ, A.; NORDLUND, M.; BĚLKA, M.; LÍZAL, F.; JEDELSKÝ, J.; ELCNER, J.; JÍCHA, M.; GEURTS, B.

Vydáno

1. 3. 2018

Nakladatel

ELSEVIER SCI LTD

Místo

ENGLAND

ISSN

0021-8502

Periodikum

JOURNAL OF AEROSOL SCIENCE

Ročník

115

Číslo

1

Stát

Spojené království Velké Británie a Severního Irska

Strany od

29

Strany do

45

Strany počet

17

URL

http://www.sciencedirect.com/science/article/pii/S0021850216302968?via%3Dihub

BibTex

@article{BUT140968,
  author="E.M.A. {frederix} and Arkadiusz {Kuczaj} and Markus {Nordlund} and Miloslav {Bělka} and František {Lízal} and Jan {Jedelský} and Jakub {Elcner} and Miroslav {Jícha} and B.J. {Geurts}",
  title="Simulation of size-dependent aerosol deposition in a realistic model
of the upper human airways",
  journal="JOURNAL OF AEROSOL SCIENCE",
  year="2018",
  volume="115",
  number="1",
  pages="29--45",
  doi="10.1016/j.jaerosci.2017.10.007",
  issn="0021-8502",
  url="http://www.sciencedirect.com/science/article/pii/S0021850216302968?via%3Dihub"
}