Detail publikace

Effect of Hyaluronic Acid on Friction of Articular Cartilage

REBENDA, D. ČÍPEK, P. NEČAS, D. VRBKA, M. HARTL, M.

Originální název

Effect of Hyaluronic Acid on Friction of Articular Cartilage

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

Intra-articular injections of hyaluronic acid based solutions are gaining popularity as a treatment option for non-operative management of patients with degenerative joint diseases. Although there is a plenty of evidence for lowering of friction in large human joints by exogenous hyaluronic acid, the physical phenomenon standing behind these results has not been clarified yet. This leads to large dispersion in effectiveness and duration in action of viscosupplementation as a treatment for osteoarthritis and; subsequently, to disparity between the view of practitioners and recent procedures questioning or disregarding the efficiency of hyaluronic acid injections. In this study, the changes in friction between intact porcine cartilage and glass plate during reciprocating sliding tests were observed to better understand interaction between hyaluronic acid and synovial fluid components. Contact was lubricated with protein solutions both with and without addition of hyaluronic acid. The effectiveness of proteins and influence of hyaluronic acid on friction are discussed.

Klíčová slova

articular cartilage, synovial fluid, friction, hyaluronic acid, viscosupplementation

Autoři

REBENDA, D.; ČÍPEK, P.; NEČAS, D.; VRBKA, M.; HARTL, M.

Vydáno

14. 5. 2018

Nakladatel

Institute of Theretical and Applied Mechanics of the Czech Academy of Sciences

Místo

Praha

ISBN

978-80-86246-91-8

Kniha

Engineering Mechanics 2018

Edice

First

Strany od

709

Strany do

712

Strany počet

4

URL

http://www.engmech.cz/improc/2018/709.pdf

BibTex

@inproceedings{BUT149021,
  author="David {Rebenda} and Pavel {Čípek} and David {Nečas} and Martin {Vrbka} and Martin {Hartl}",
  title="Effect of Hyaluronic Acid on Friction of Articular Cartilage",
  booktitle="Engineering Mechanics 2018",
  year="2018",
  series="First",
  pages="709--712",
  publisher="Institute of Theretical and Applied Mechanics of the Czech Academy of Sciences",
  address="Praha",
  doi="10.21495/91-8-709",
  isbn="978-80-86246-91-8",
  url="http://www.engmech.cz/improc/2018/709.pdf"
}