2D-Dichalkogenide Quantum Dots for Hydrogen Peroxide Sensing

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The influence of 2D-nanomaterial quantum dots on hydrogen peroxide sensing Reactive oxygen species (ROS) are important signal molecules that play crucial role in cellular metabolism. As one of them, the hydrogen peroxide (H2O2) is under physiological conditions converted into water and oxygen. Under pathological conditions, the cell is unable to control this process, which results in oxidative stress leading to damage of cellular structures. The concentration of H2O2 which is produced by such cells is on nanomolar scale. Currently used sensors that are able to measure these amounts are expensive. This work is focused on preparation of various 2D-nanomaterial quantum dots, their use for screen printed electrode (SPE) modifications and the examination of resulting detection properties. Based on previous research, materials from the family of transition metal dichalkogenides were chosen (MoS2, MoSe2, WS2, WSe2). Compared to platinum nanoparticles, which can be used for nanomolar H2O2 sensing, used materials are cheaper and easier to produce. 2D-nanomaterial quantum dots were produced by liquid phase exfoliation. This technique requires very low amounts of source material (0.1 – 1 g). Nanoparticles were characterized using atomic force microscopy. Modification of SPE was done by dropcasting the suspension on working electrode. To determine the effect of individual modifications, multiple measurements utilizing cyclic voltammetry and standard solutions of Ferro-Ferricyanide, phosphate buffer saline and H2O2 were carried. After the measurement, the data were visualized and the impact on detection properties of SPE was assessed.

QUANTUM DOTS, DICHALKOGENIDES, HYDROGEN PEROXIDE, SENSING, SCREEN PRINTED ELECTRODES

ZAHRADNÍČEK, R.; BÍLEK, O.; ZDRAŽIL, L.; SOFER, Z.; LACINA, K.; HUBÁLEK, J.; FOHLEROVÁ, Z.

18. 10. 2018