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MACHÁČEK, O. KUBÍK, M. ROUPEC, J. STRECKER, Z. MAZŮREK, I.
Originální název
MICRO-FLUIDIC SYSTEM WITH GROOVED POLE PIECES OF MAGNETIC CIRCUIT
Typ
článek ve sborníku ve WoS nebo Scopus
Jazyk
angličtina
Originální abstrakt
Micro-fluidic systems are used in approximately 30 years for detect or separate biological molecules which are contain in a biological medium (blood, serum, etc.). The technique of separation is based on magnetic force acting on the magnetic particles which are added to the medium. One way to increase separation efficiency is to optimize the magnetic circuit. Two versions of magnetic circuit for the micro-fluidic system are designed, tested and compared in this study. The first of them has solid pole pieces (without grooves), the second one is provided with grooves which are oriented perpendicular to the direction of a fluid flow through the system. A suitable geometry of the grooves was chosen using a FEM model which is verified by measurement. Hypothesis that the grooved pole pieces ensure higher amount of captured particles in the system in comparison with the case of solid pole pieces was confirmed. But, the comparison of the captured particles amount was made just visually. Therefore, the amount of particles which are washout during a flow test should be evaluated by more quantifiable method in future study, for example using Beer-Lambert law.
Klíčová slova
Micro-fluidic system, immunoassay, magnetic circuit, grooved pole pieces
Autoři
MACHÁČEK, O.; KUBÍK, M.; ROUPEC, J.; STRECKER, Z.; MAZŮREK, I.
Vydáno
14. 5. 2018
Nakladatel
Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences
Místo
Prague
ISBN
978-80-86246-88-8
Kniha
ENGINEERING MECHANICS 2018
Edice
24th INTERNATIONAL CONFERENCE
ISSN
1805-8256
Periodikum
Engineering Mechanics ....
Ročník
24
Číslo
1
Stát
Česká republika
Strany od
521
Strany do
524
Strany počet
4
BibTex
@inproceedings{BUT151987, author="Ondřej {Macháček} and Michal {Kubík} and Jakub {Roupec} and Zbyněk {Strecker} and Ivan {Mazůrek}", title="MICRO-FLUIDIC SYSTEM WITH GROOVED POLE PIECES OF MAGNETIC CIRCUIT", booktitle="ENGINEERING MECHANICS 2018", year="2018", series="24th INTERNATIONAL CONFERENCE", journal="Engineering Mechanics ....", volume="24", number="1", pages="521--524", publisher="Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences", address="Prague", isbn="978-80-86246-88-8", issn="1805-8256" }