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BRÁZDA, V. JAGELSKÁ, E. B. KOLOMAZNÍK, J. LÝSEK, J. KAURA, P. BARTAS, M. COUFAL, J. ŠŤASTNÝ, J.
Originální název
DNA analyser, a new powerful tool to identify and analyse local DNA structures in genomes
Typ
abstrakt
Jazyk
angličtina
Originální abstrakt
Local DNA structures play important roles in the regulation of basic biological processes. Whilst computational approaches to identify these structures are available, the number of easily accessible and userfriendly tools is limited, especially for analysis of different types of local structures within long nucleotide sequences. We have developed a webbased server, DNA analyser, which is a userfriendly application for analysing local DNA structures. At first we implemented a tool for analyses of inverted repeats in various nucleic acids sequences including genome sequences and oligonucleotides. It allows users to search and retrieve desired gene/nucleotide sequence entries from the NCBI databases, and provides data on length, sequence, locations and energy required for cruciform formation. We have recently included new tools for analyses of quadruplexforming sequences – an interactive webversion of the G4hunter algorithm as well as a tool to search for p53 target sequences. DNA analyser also features an interactive graphical representation of the distribution of local DNA structures and options for sorting and data export. DNA analyser allows whole genome analyses and it is freely available at http://bioinformatics.ibp.cz
Klíčová slova
DNA analyser, DNA structures, G4hunter algorithm
Autoři
BRÁZDA, V.; JAGELSKÁ, E. B.; KOLOMAZNÍK, J.; LÝSEK, J.; KAURA, P.; BARTAS, M.; COUFAL, J.; ŠŤASTNÝ, J.
Vydáno
6. 7. 2019
ISSN
2211-5463
Periodikum
FEBS Open Bio
Ročník
9
Číslo
S1
Stát
Spojené království Velké Británie a Severního Irska
Strany od
149
Strany do
Strany počet
1
URL
https://febs.onlinelibrary.wiley.com/toc/22115463/2019/9/S1
BibTex
@misc{BUT157848, author="BRÁZDA, V. and JAGELSKÁ, E. B. and KOLOMAZNÍK, J. and LÝSEK, J. and KAURA, P. and BARTAS, M. and COUFAL, J. and ŠŤASTNÝ, J.", title="DNA analyser, a new powerful tool to identify and analyse local DNA structures in genomes", year="2019", journal="FEBS Open Bio", volume="9", number="S1", pages="149--149", doi="10.1002/2211-5463.12675", issn="2211-5463", url="https://febs.onlinelibrary.wiley.com/toc/22115463/2019/9/S1", note="abstract" }