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Detail publikace
Zhu, HL. Zhang, HQ. Ni, S. Korabecna, M. Yobas, L. Neuzil, P.
Originální název
The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
Infectious diseases, such as the most recent case of coronavirus disease 2019, have brought the prospect of point-of-care (POC) diagnostic tests into the spotlight. A rapid, accurate, low-cost, and easy-to-use test in the field could stop epidemics before they develop into full-blown pandemics. Unfortunately, despite all the advances, it still does not exist. Here, we critically review the limited number of prototypes demonstrated to date that is based on a polymerase chain reaction (PCR) and has come close to fulfill this vision. We summarize the requirements for the POC PCR tests and then go on to discuss the PCR product-detection methods, the integration of their functional components, the potential applications, and other practical issues related to the implementation of lab-on-a-chip technologies. We conclude our review with a discussion of the latest findings on nucleic acid-based diagnosis. (C) 2020 Elsevier B.V. All rights reserved.
Klíčová slova
COVID-19 diagnoses; Polymerase chain reaction; Microfluidics; Miniaturization; Point of care; Future of PCR
Autoři
Zhu, HL.; Zhang, HQ.; Ni, S.; Korabecna, M.; Yobas, L.; Neuzil, P.
Vydáno
1. 9. 2020
Nakladatel
ELSEVIER SCI LTD
Místo
OXFORD
ISSN
0165-9936
Periodikum
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
Ročník
130
Číslo
115984
Stát
Spojené království Velké Británie a Severního Irska
Strany od
Strany do
Strany počet
13
URL
https://www.sciencedirect.com/science/article/pii/S0165993620302132?casa_token=Z2ZbtTb1LWcAAAAA:u6pRqpDLw8a4YLRIgJDrxE5ECMwLBKGAYLVU_7xizQgoBIyT8yQWdit6se91jm0vDmQz9Cz97A
BibTex
@article{BUT165708, author="Zhu, HL. and Zhang, HQ. and Ni, S. and Korabecna, M. and Yobas, L. and Neuzil, P.", title="The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond", journal="TRAC-TRENDS IN ANALYTICAL CHEMISTRY", year="2020", volume="130", number="115984", pages="115984--115984", doi="10.1016/j.trac.2020.115984", issn="0165-9936", url="https://www.sciencedirect.com/science/article/pii/S0165993620302132?casa_token=Z2ZbtTb1LWcAAAAA:u6pRqpDLw8a4YLRIgJDrxE5ECMwLBKGAYLVU_7xizQgoBIyT8yQWdit6se91jm0vDmQz9Cz97A" }