Detail publikace

Multiscale experimental evaluation of agarose-based semi-interpenetrating polymer network hydrogels as materials with tunable rheological and transport performance

TRUDIČOVÁ, M. SMILEK, J. KALINA, M. SMILKOVÁ, M. ADÁMKOVÁ, K. HRUBANOVÁ, K. KRZYŽÁNEK, V. SEDLÁČEK, P.

Originální název

Multiscale experimental evaluation of agarose-based semi-interpenetrating polymer network hydrogels as materials with tunable rheological and transport performance

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This study introduces an original concept in the development of hydrogel materials for controlled release of charged organic compounds based on semi-interpenetrating polymer networks composed by an inert gel-forming polymer component and interpenetrating linear polyelectrolyte with specific binding affinity towards the carried active compound. As it is experimentally illustrated on the prototype hydrogels prepared from agarose interpenetrated by poly(styrene sulfonate) (PSS) and alginate (ALG), respectively, the main benefit brought by this concept is represented by the ability to tune the mechanical and transport performance of the material independently via manipulating the relative content of the two structural components. A unique analytical methodology is proposed to provide complex insight into composition–structure– performance relationships in the hydrogel material combining methods of analysis on the macroscopic scale, but also in the specific microcosms of the gel network. Rheological analysis has confirmed that the complex modulus of the gels can be adjusted in a wide range by the gelling component (agarose) with negligible effect of the interpenetrating component (PSS or ALG). On the other hand, the content of PSS as low as 0.01 wt.% of the gel resulted in a more than 10-fold decrease of diffusivity of model-charged organic solute (Rhodamine 6G).

Klíčová slova

hydrogels; semi-interpenetrating polymer networks; controlled release systems; rheology; diffusion; cryo-scanning electron microscopy

Autoři

TRUDIČOVÁ, M.; SMILEK, J.; KALINA, M.; SMILKOVÁ, M.; ADÁMKOVÁ, K.; HRUBANOVÁ, K.; KRZYŽÁNEK, V.; SEDLÁČEK, P.

Vydáno

31. 10. 2020

Nakladatel

MDPI

Místo

Basel, Switzerland

ISSN

2073-4360

Periodikum

Polymers

Ročník

12

Číslo

11

Stát

Švýcarská konfederace

Strany od

1

Strany do

25

Strany počet

25

URL

https://www.mdpi.com/2073-4360/12/11/2561

Plný text v Digitální knihovně

http://hdl.handle.net/11012/195667

BibTex

@article{BUT166087,
  author="Monika {Trudičová} and Jiří {Smilek} and Michal {Kalina} and Marcela {Smilková} and Kateřina {Adámková} and Kamila {Hrubanová} and Vladislav {Krzyžánek} and Petr {Sedláček}",
  title="Multiscale experimental evaluation of agarose-based semi-interpenetrating polymer network hydrogels as materials with tunable rheological and transport performance",
  journal="Polymers",
  year="2020",
  volume="12",
  number="11",
  pages="1--25",
  doi="10.3390/polym12112561",
  issn="2073-4360",
  url="https://www.mdpi.com/2073-4360/12/11/2561"
}

Dokumenty

polymers-12-02561-v2.pdf