Detail publikace

The distribution of antibiotic resistance genes in chicken gut microbiota commensals

JUŘICOVÁ, H. MATIAŠOVICOVÁ, J. KUBASOVÁ, T. ČEJKOVÁ, D. RYCHLÍK, I.

Originální název

The distribution of antibiotic resistance genes in chicken gut microbiota commensals

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Antibiotic resistance in bacterial pathogens or several indicator bacteria is commonly studied but the extent of antibiotic resistance in bacterial commensals colonising the intestinal tract is essentially unknown. In this study, we aimed to investigate the presence of horizontally acquired antibiotic resistance genes among chicken gut microbiota members in 259 isolates with known whole genomic sequences. Altogether 124 isolates contained at least one gene coding for antibiotic resistance. Genes coding for the resistance to tetracyclines (detected in 101 isolates), macrolide-lincosamide-streptogramin B antibiotics (28 isolates) and aminoglycosides (25 isolates) were the most common. The most frequent tetracycline resistance genes were tet(W), tet(32), tet(O) and tet(Q). Lachnospiraceae and Ruminococcaceae frequently encoded tet(W). Lachnospiraceae commonly coded also for tet(32) and tet(O). The tet(44) gene was associated with Erysipelotrichaceae and tet(Q) was detected in the genomes of Bacteroidaceae and Porphyromonadaceae. Without any bias we have shown that antibiotic resistance is quite common in gut commensals. However, a comparison of codon usage showed that the above-mentioned families represent the most common current reservoirs but probably not the original host of the detected resistances.

Klíčová slova

Antibiotic resistance, chicken gut commensals

Autoři

JUŘICOVÁ, H.; MATIAŠOVICOVÁ, J.; KUBASOVÁ, T.; ČEJKOVÁ, D.; RYCHLÍK, I.

Vydáno

8. 2. 2021

Nakladatel

Springer Nature

Místo

BERLIN

ISSN

2045-2322

Periodikum

Scientific Reports

Ročník

11

Číslo

1

Stát

Spojené království Velké Británie a Severního Irska

Strany od

1

Strany do

10

Strany počet

10

URL

https://www.nature.com/articles/s41598-021-82640-3

Plný text v Digitální knihovně

http://hdl.handle.net/11012/200994

BibTex

@article{BUT172114,
  author="Helena {Juřicová} and Jitka {Matiašovicová} and Tereza {Kubasová} and Darina {Čejková} and Ivan {Rychlík}",
  title="The distribution of antibiotic resistance genes in chicken gut microbiota commensals",
  journal="Scientific Reports",
  year="2021",
  volume="11",
  number="1",
  pages="1--10",
  doi="10.1038/s41598-021-82640-3",
  issn="2045-2322",
  url="https://www.nature.com/articles/s41598-021-82640-3"
}