Detail publikace

In vitro structured tree model of the peripheral vascular network

KOHÚT, J. JAGOŠ, J. FORMÁNEK, M. BURŠA, J.

Originální název

In vitro structured tree model of the peripheral vascular network

Typ

článek ve sborníku mimo WoS a Scopus

Jazyk

angličtina

Originální abstrakt

The peripheral arterial system consists of small arteries and arterioles, further branching into capillaries. This complex system could be faithfully represented by an asymmetrically structured tree. Such an approach has been used solely in computational analyses, for instance, 1D fluid-structure interaction simulations or multiscale modelling (3D/1D). In vitro flow phantom studies incorporate only pure resistance or two-element Windkessel to mimic the periphery. Thus, the flow and pressure waveforms in these in vitro studies do not qualitatively correspond to those measured in vivo and consequently nor do the input impedance of the periphery, which is rarely shown. To consider the frequency-dependent input impedance of the tree close to that observed in vivo, we created an experimental circuit. It comprises a peristaltic pump as a source of a physiological waveform, an asymmetric structured tree model constructed from commonly available silicon tubes, and a measurement technique for obtaining the input impedance. A good agreement between mathematical and experimental data was found despite some inaccuracies and imperfections in the assembled tree. Therefore, the mathematical model can serve as a design tool for individual in vitro structured tree models representing different peripheral sites. Consequently, the in vitro model could be included in phantom studies as a more realistic boundary condition.

Klíčová slova

mathematical model; experimental circuit; structured tree model; peripheral vascular network

Autoři

KOHÚT, J.; JAGOŠ, J.; FORMÁNEK, M.; BURŠA, J.

Vydáno

8. 11. 2021

Nakladatel

University of West Bohemia

Místo

Plzeň

ISBN

978-80-261-1059-0

Kniha

PROCEEDINGS OF COMPUTATIONAL MECHANICS 2021

Strany od

118

Strany do

121

Strany počet

4

URL

https://dspace5.zcu.cz/bitstream/11025/46012/2/CM2021_Conference_Proceedings-128-131.pdf

BibTex

@inproceedings{BUT180255,
  author="Jiří {Kohút} and Jiří {Jagoš} and Martin {Formánek} and Jiří {Burša}",
  title="In vitro structured tree model of the peripheral vascular network",
  booktitle="PROCEEDINGS OF COMPUTATIONAL MECHANICS 2021",
  year="2021",
  pages="118--121",
  publisher="University of West Bohemia",
  address="Plzeň",
  isbn="978-80-261-1059-0",
  url="https://dspace5.zcu.cz/bitstream/11025/46012/2/CM2021_Conference_Proceedings-128-131.pdf"
}