Detail publikace

Prodromal Diagnosis of Lewy Body Diseases Based on the Assessment of Graphomotor and Handwriting Difficulties

GALÁŽ, Z. MEKYSKA, J. MUCHA, J. ZVONČÁK, V. SMÉKAL, Z. FAÚNDEZ ZANUY, M. BRABENEC, L. MORÁVKOVÁ, I. REKTOROVÁ, I.

Originální název

Prodromal Diagnosis of Lewy Body Diseases Based on the Assessment of Graphomotor and Handwriting Difficulties

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

angličtina

Originální abstrakt

To this date, studies focusing on the prodromal diagnosis of Lewy body diseases (LBDs) based on quantitative analysis of graphomotor and handwriting difficulties are missing. In this work, we enrolled 18 subjects diagnosed with possible or probable mild cognitive impairment with Lewy bodies (MCI-LB), 7 subjects having more than 50% probability of developing Parkinson’s disease (PD), 21 subjects with both possible/probable MCI-LB and probability of PD > 50%, and 37 age- and gender-matched healthy controls (HC). Each participant performed three tasks: Archimedean spiral drawing (to quantify graphomotor difficulties), sentence writing task (to quantify handwriting difficulties), and pentagon copying test (to quantify cognitive decline). Next, we parameterized the acquired data by various temporal, kinematic, dynamic, spatial, and task-specific features. And finally, we trained classification models for each task separately as well as a model for their combination to estimate the predictive power of the features for the identification of LBDs. Using this approach we were able to identify prodromal LBDs with 74% accuracy and showed the promising potential of computerized objective and non-invasive diagnosis of LBDs based on the assessment of graphomotor and handwriting difficulties.

Klíčová slova

Lewy body diseases;Online handwriting;Graphomotor difficulties;Handwriting difficulties;Quantitative assessment

Autoři

GALÁŽ, Z.; MEKYSKA, J.; MUCHA, J.; ZVONČÁK, V.; SMÉKAL, Z.; FAÚNDEZ ZANUY, M.; BRABENEC, L.; MORÁVKOVÁ, I.; REKTOROVÁ, I.

Vydáno

10. 12. 2022

Nakladatel

Springer, Cham

ISBN

978-3-031-19745-1

Kniha

Intertwining Graphonomics with Human Movements

Edice

1

Číslo edice

13424

Strany od

255

Strany do

268

Strany počet

14

URL

https://link.springer.com/chapter/10.1007/978-3-031-19745-1_19

BibTex

@inproceedings{BUT180581,
  author="Zoltán {Galáž} and Jiří {Mekyska} and Ján {Mucha} and Vojtěch {Zvončák} and Zdeněk {Smékal} and Marcos {Faúndez Zanuy} and Luboš {Brabenec} and Ivona {Morávková} and Irena {Rektorová}",
  title="Prodromal Diagnosis of Lewy Body Diseases Based on the Assessment of Graphomotor and Handwriting Difficulties",
  booktitle="Intertwining Graphonomics with Human Movements",
  year="2022",
  series="1",
  number="13424",
  pages="255--268",
  publisher="Springer, Cham",
  doi="10.1007/978-3-031-19745-1\{_}19",
  isbn="978-3-031-19745-1",
  url="https://link.springer.com/chapter/10.1007/978-3-031-19745-1_19"
}