Detail publikace

Role of ciliopathy protein TMEM107 in eye development: insights from a mouse model and retinal organoid

DUBAIC M., PESKOVA L., HAMPL M., WEISSOVA K., CELIKER C., SHYLO N., HRUBA E., KAVKOVA M., ZIKMUND T., WEATHERBOO S., KAISER J., BARTA T., BUCHTOVA M.

Originální název

Role of ciliopathy protein TMEM107 in eye development: insights from a mouse model and retinal organoid

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Primary cilia, enriched in receptors and signaling molecules, serve as vital signaling hubs responsive to stimuli and are implicated in human diseases like retinopathies. TMEM107, localized to the transition zone of primary cilia, is linked to conditions such as Joubert and Meckel–Gruber syndromes, and its deficiency hinders cilia formation and early vertebrate eye development in retinal organoids.

Klíčová slova

TMEM107, ciliopathy, eye development, cell biology

Autoři

DUBAIC M., PESKOVA L., HAMPL M., WEISSOVA K., CELIKER C., SHYLO N., HRUBA E., KAVKOVA M., ZIKMUND T., WEATHERBOO S., KAISER J., BARTA T., BUCHTOVA M.

Vydáno

20. 10. 2023

Nakladatel

Life Science Alliance

ISSN

2575-1077

Periodikum

Life Science Alliance

Ročník

6

Číslo

12

Stát

Spojené státy americké

Strany od

1

Strany do

16

Strany počet

16

URL

https://www.life-science-alliance.org/content/6/12/e202302073

Plný text v Digitální knihovně

http://hdl.handle.net/11012/245089

BibTex

@article{BUT184959,
  author="Marija {Dubaic} and Lucie {Pešková} and Marek {Hampl} and Kamila {Weissová} and Canan {Celiker} and Natalya A. {Shylo} and Eva {Hrubá} and Michaela {Kavková} and Tomáš {Zikmund} and Scott Donald {Weatherbee} and Jozef {Kaiser} and Tomáš {Bárta} and Marcela {Buchtová}",
  title="Role of ciliopathy protein TMEM107 in eye development: insights from a mouse model and retinal organoid",
  journal="Life Science Alliance",
  year="2023",
  volume="6",
  number="12",
  pages="1--16",
  doi="10.26508/lsa.202302073",
  issn="2575-1077",
  url="https://www.life-science-alliance.org/content/6/12/e202302073"
}