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HEMZAL, M.
Originální název
A simplified 2D model of reentry in cardiac tissue using the FHN model.
Typ
článek ve sborníku mimo WoS a Scopus
Jazyk
angličtina
Originální abstrakt
Spatial inhomogeneities in cardiac tissue, such as fibroblast clumps, scar tissue, or ischemic tissue, are well known to be sources of reentrant activity in the muscle that can induce certain cardiac arrhythmias. In this paper, two models of cardiac tissue were investigated. First, a homogeneous cardiac tissue model is introduced, in which the normal action potential distribution is shown. The second model with spatial inhomogeneity(regional ischemia, scar tissue, fibroblast clumps) that induces the reentrant activity of the cardiac tissue. The distribution of the action potential was solved in the cardiac tissue using a monodomain model with a modified FitzHugh-Nagumo (FHN) ionic model. To simulate the inhomogeneity in the tissue, one parameter of the FHN model that accounts for the excitability of the cell was modified, as well as the diffusion coefficient in the reaction-diffusion equation. This modification led to the reentrant activity in the second model. This simplified model can be used to study arrhythmogenic waves induced by spatial inhomogeneities in cardiac tissue.
Klíčová slova
FEM, FitzHugh-Nagumo, monodomain model, reentry
Autoři
Vydáno
23. 4. 2023
Nakladatel
Brno University of Technology, Faculty of Electrical Engineering
Místo
Brno
ISBN
ISBN 978-80-214-6153
Kniha
Proceedings I of the 29th Conference STUDENT EEICT 2023
Edice
1.
Strany od
284
Strany do
288
Strany počet
5
URL
https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2023_sbornik_1.pdf
BibTex
@inproceedings{BUT185065, author="Martin {Hemzal}", title="A simplified 2D model of reentry in cardiac tissue using the FHN model.", booktitle="Proceedings I of the 29th Conference STUDENT EEICT 2023", year="2023", series="1.", pages="284--288", publisher="Brno University of Technology, Faculty of Electrical Engineering", address="Brno", isbn="ISBN 978-80-214-6153", url="https://www.eeict.cz/eeict_download/archiv/sborniky/EEICT_2023_sbornik_1.pdf" }