Detail publikace
Adaptability of Electrospun PVDF Nanofibers in Bone Tissue Engineering
HAVLÍKOVÁ, T. PAPEŽ, N. FOHLEROVÁ, Z. KASPAR, P. DALLAEV, R. ČÁSTKOVÁ, K. ŢĂLU, Ş.
Originální název
Adaptability of Electrospun PVDF Nanofibers in Bone Tissue Engineering
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
This study focused on the development of a suitable synthetic polymer scaffold for bone tissue engineering applications within the biomedical field. The investigation centered on electrospun polyvinylidene fluoride (PVDF) nanofibers, examining their intrinsic properties and biocompatibility with the human osteosarcoma cell line Saos-2. The influence of oxygen, argon, or combined plasma treatment on the scaffold’s characteristics was explored. A comprehensive design strategy is outlined for the fabrication of a suitable PVDF scaffold, encompassing the optimization of electrospinning parameters with rotating collector and plasma etching conditions to facilitate a subsequent osteoblast cell culture. The proposed methodology involves the fabrication of the PVDF tissue scaffold, followed by a rigorous series of fundamental analyses encompassing the structural integrity, chemical composition, wettability, crystalline phase content, and cell adhesion properties.
Klíčová slova
biocompatibility; bone tissue engineering; bone regeneration; cell–substrate interactions; electrospinning; nanofiber fabrication; osteoblasts; piezoelectric polymer; plasma treatment; polyvinylidene fluoride; scaffold
Autoři
HAVLÍKOVÁ, T.; PAPEŽ, N.; FOHLEROVÁ, Z.; KASPAR, P.; DALLAEV, R.; ČÁSTKOVÁ, K.; ŢĂLU, Ş.
Vydáno
25. 1. 2025
Nakladatel
MDPI
Místo
BASEL
ISSN
2073-4360
Periodikum
Polymers
Ročník
17
Číslo
3
Stát
Švýcarská konfederace
Strany počet
23
URL
BibTex
@article{BUT196640,
author="Tereza {Havlíková} and Nikola {Papež} and Zdenka {Fohlerová} and Pavel {Kaspar} and Rashid {Dallaev} and Klára {Částková} and Ştefan {Ţălu}",
title="Adaptability of Electrospun PVDF Nanofibers in Bone Tissue Engineering",
journal="Polymers",
year="2025",
volume="17",
number="3",
pages="23",
doi="10.3390/polym17030330",
issn="2073-4360",
url="https://www.mdpi.com/2073-4360/17/3/330"
}